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  • A methodological discrepancy exists in the hydration assessment literature regarding the establishment of euhydration, as some investigations utilize a prehydration technique, while others do not (overnight fluid/food fast). However, the degree that plasma osmolality (Posm) dilutes when using the pre-hydration method and how body mass/composition might influence the results is not known. Thirty subjects (22 M, 8 F; 20 ± 2 years (mean ± SD); 1.8 ± 0.1 m; 75.8 ± 13.5 kg) had P osm measured after an 8-h food and fluid fast (overnight fast) and 90 min after a 500-mL (4-9 mL/kg) water bolus (prehydration). From pre- to post-bolus, participants' P osm declined from 297 ± 3.5 to 295 ± 3.8 mmol/kg (p<0.05; Δ -1.7 ± 3.5 mmol/kg). One-third of the sample diluted to more than -3 mmol/kg. The effect of body mass on P osm dilution was investigated by comparing dilution in the ten lightest (62.8 ± 3.4 kg) and heaviest (92.0 ± 9.8 kg) participants; however, the change between the light (Δ -1.9 ± 3.8 mmol/kg) versus heavy groups (Δ -1.1 ± 3.0 mmol/kg) was not different (p>0.05). The correlation between body mass or total body water and change in P osm was weak (p>0.05), as was the correlation between relative fluid intake based on mass and change in P osm (p>0.05). The two methodologies appear to produce similar P osm values when measured in most individuals. However, the potential for significant dilution (>3 mmol/kg) should be considered when choosing the pre-hydration methodology. © Springer-Verlag (outside the USA) 2011.

Last update from database: 3/13/26, 4:15 PM (UTC)

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