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Individuals with autism spectrum disorder (ASD) often have co-morbid anxiety and depression. Alexithymia and emotion regulation difficulties are commonly seen in individuals with ASD and in mood disorders. We hypothesized that alexithymia and emotional regulation would mediate the relationship between autistic features and anxiety/depression symptom severity. We collected data about emotional regulation, alexithymia, autistic symptoms and depression/anxiety in a sample of 64 young adults with ASD. We constructed two serial multiple mediator models, using autistic features as the independent variable and anxiety/depression symptoms as outcome variables. The serial relationship between alexithymia and emotional regulation mediated associations between autistic features and depression and anxiety, separately. The findings suggest that targeting alexithymia may benefit therapies designed to alleviate mood disorders in ASD.
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Autism spectrum disorder (ASD) affects approximately 1 in 59 children, but there are currently no biomedical treatments available that target the core symptoms (1). Preliminary evidence suggests that repetitive transcranial magnetic stimulation (rTMS) may have the potential to alleviate difficulties experienced by individuals with ASD (2). The evidence supporting the use of rTMS for ASD has led researchers in the field to form a consensus group that has met annually since 2014. Here we summarize discussions from the most recent meeting in May 2017, including recommendations for future research directions.