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The studies reviewed here reflect many important aspects of the onset, course, and outcome of schizophrenia; that is, premorbid factors, childhood and late-life onset, the positive-negative syndrome dichotomy, co-occurring substance abuse, outcome research, and theoretical issues. Unsurprisingly, heterogeneity of course and outcome emerges as a major theme., (C) Lippincott-Raven Publishers.
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The authors hypothesized that schizophrenic communication disturbances reflect specific cognitive deficits in the areas of working memory and attention. They examined the cognitive correlates of communication disturbances, as measured by linguistic reference performance, in schizophrenic (n = 48), bipolar (n = 24), and nonpsychiatric control (n = 23) individuals. Reference performance ratings in the schizophrenic patients were associated with scores on tests of working memory and attention and were not related to performance on concept formation or verbal fluency tests. In contrast, in the bipolar and nonpsychiatric individuals, reference performance was associated with concept formation and verbal fluency test scores but was not related to performance on tests of working memory. Implications with respect to the processes underlying schizophrenic communication disturbances are discussed.