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Obstructive sleep apnea syndrome (OSAS) is a pervasive disorder with an incidence estimated at 5–14 percent among adults aged 30–70 years. It carries significant morbidity and mortality risk from cardiovascular disease, including ischemic heart disease, atrial fibrillation, and cerebrovascular disease, and risks related to excessive daytime sleepiness. The gold standard for diagnosis of OSAS is the polysomnography (PSG) test which requires overnight evaluation in a sleep laboratory and expensive infrastructure, which renders it unsuitable for mass screening and diagnosis. Alternatives such as home sleep testing need patients to wear diagnostic instruments overnight, but accuracy continues to be suboptimal while access continues to be a barrier for many. Hence, there is a continued significant underdiagnosis and under-recognition of sleep apnea in the community, with at least one study suggesting that 80–90% of middle-aged adults with moderate to severe sleep apnea remain undiagnosed. Recently, we have seen a surge in applications of artificial intelligence and neural networks in healthcare diagnostics. Several studies have attempted to examine its application in the diagnosis of OSAS. Signals included in data analytics include Electrocardiogram (ECG), photo-pletysmography (PPG), peripheral oxygen saturation (SpO2), and audio signals. A different approach is to study the application of machine learning to use demographic and standard clinical variables and physical findings to try and synthesize predictive models with high accuracy in assisting in the triage of high-risk patients for sleep testing. The current paper will review this latter approach and identify knowledge gaps that may serve as potential avenues for future research.

Sleep apnea is a sleeping disorder affecting more than 20 % of all American adults, associated with intermittent air passageway obstruction during sleep. This results in intermittent hypoxia, sympathetic activation, and an interruption of sleep with various health consequences. The diagnosis of sleep apnea traditionally involves the performance of overnight polysomnography, where oxygen, heart rate, and breathing, among other physiologic variables, are continuously monitored during sleep at a sleep center. However, these sleep studies are expensive and impose access issues, given the number of patients who need to be diagnosed. There is hence utility in having an effective triage system to screen for OSA to utilize polysomnography better. In this study, we plan to explore using several machine learning algorithms to utilize pre-screening symptoms to diagnose obstructive sleep apnea (OSA). Per our experimental results, it was found that Decision Tree Classifier (DTC) and Random Forest (RF) provided the highest classification accuracies compared to other algorithms such as Logistic Regression (LR), Support Vector Machines (SVM), Gradient Boosting Classifier (GBC), Gaussian Naive Bayes (GNB), K Neighbors Classifier (KNC), and Artificial Neural Networks (ANN).

In this paper, we provide a consistent, inexpensive, and easy to use graphical user interface (GUI) smart phone application named Sleep Apnea Screener (SAS) that can diagnosis Obstructive Sleep Apnea (OSA) based on demographic data such as: gender, age, height, BMI, neck circumference, waist, etc., allowing a tentative diagnosis of OSA without the need for overnight tests. The developed smart phone application can diagnosis sleep apnea using a model trained with 620 samples collected from a sleep center in Corpus Christi, TX. Two machine learning classifiers (i.e., Logistic Regression (LR) and Support Vector Machine (SVM)) were used to diagnosis OSA. Our preliminary results show that at-home OSA screening is indeed possible, and that our application is effective method for covering large numbers of undiagnosed cases.

Background: In the United States, chronic obstructive pulmonary disease (COPD) is a significant cause of mortality. As far as we know, it is a chronic, inflammatory lung condition that cuts off airflow to the lungs. Many symptoms have been reported for such a disease: breathing problems, coughing, wheezing, and mucus production. Patients with COPD might be at risk, since they are more susceptible to heart disease and lung cancer. Methods: This study reviews COPD diagnosis utilizing various machine learning (ML) classifiers, such as Logistic Regression (LR), Gradient Boosting Classifier (GBC), Support Vector Machine (SVM), Gaussian Naïve Bayes (GNB), Random Forest Classifier (RFC), K-Nearest Neighbors Classifier (KNC), Decision Tree (DT), and Artificial Neural Network (ANN). These models were applied to a dataset comprising 1603 patients after being referred for a pulmonary function test. Results: The RFC has achieved superior accuracy, reaching up to 82.06% in training and 70.47% in testing. Furthermore, it achieved a maximum F score in training and testing with an ROC value of 0.0.82. Conclusions: The results obtained with the utilized ML models align with previous work in the field, with accuracies ranging from 67.81% to 82.06% in training and from 66.73% to 71.46% in testing.

Regrettably, a large proportion of likely patients with sleep apnea are underdiagnosed. Obstructive sleep apnea (OSA) is one of the main causes of hypertension, type II diabetes, stroke, coronary artery disease, and heart failure. OSA affects not only adults but also children where it forms one of the sources of learning disabilities for children. This study aims to provide a classification model for one of the well-known sleep disorders known as OSA, which causes a serious malady that affects both men and women. OSA affects both genders with different scope. Men versus women diagnosed with OSA are about 8:1. In this research, logistic regression (LR) and artificial neural networks were applied successfully in several classification applications with promising results, particularly in the bio-statistics area. LR was used to derive a membership probability for a potential OSA system from a range of anthropometric features including weight, height, body mass index (BMI), hip, waist, age, neck circumference, modified Friedman, snoring, Epworth sleepiness scale (ESS), sex, and daytime sleepiness. We developed two models to predict OSA, one for men and one for women. The proposed sleep apnea diagnosis model has yielded accurate classification results and possibly a prototype software module that can be used at home. These findings shall reduce the patient’s need to spend a night at a laboratory and make the study of sleep apnea to implement at home.

Obstructive sleep apnea (OSA) is a well-known sleep ailment. OSA mostly occurs due to the shortage of oxygen for the human body, which causes several symptoms (i.e., low concentration, daytime sleepiness, and irritability). Discovering the existence of OSA at an early stage can save lives and reduce the cost of treatment. The computer-aided diagnosis (CAD) system can quickly detect OSA by examining the electrocardiogram (ECG) signals. Over-serving ECG using a visual procedure is challenging for physicians, time-consuming, expensive, and subjective. In general, automated detection of the ECG signal’s arrhythmia is a complex task due to the complexity of the data quantity and clinical content. Moreover, ECG signals are usually affected by noise (i.e., patient movement and disturbances generated by electric devices or infrastructure), which reduces the quality of the collected data. Machine learning (ML) and Deep Learning (DL) gain a higher interest in health care systems due to its ability of achieving an excellent performance compared to traditional classifiers. We propose a CAD system to diagnose apnea events based on ECG in an automated way in this work. The proposed system follows the following steps: (1) remove noise from the ECG signal using a Notch filter. (2) extract nine features from the ECG signal (3) use thirteen ML and four types of DL models for the diagnosis of sleep apnea. The experimental results show that our proposed approach offers a good performance of DL classifiers to detect OSA. The proposed model achieves an accuracy of 86.25% in the validation stage.

Coronary heart disease (CHD) is the leading global cause of death, making early detection essential. While coronary angiography is the diagnostic gold standard, its invasive nature poses risks, and non-invasive symptom-based methods often lack accuracy. Machine learning-powered computer-aided diagnostic systems can effectively address challenges in clinical decisionmaking. This work presents an Evolutionary Strategy-optimized Support Vector Machine (ES-SVM) model for classifying CHD based on non-invasive test results and patient characteristics. Using the Coronary Heart Disease dataset, the proposed ESSVM demonstrated significant precision and F1-scores, as well as the accuracy of the proposed model. The results indicate that SVM performance can be significantly enhanced through evolutionary hyperparameter tuning, resulting in a reliable, noninvasive diagnostic tool for initial CAD screening and supporting early intervention techniques. © 2025 IEEE.

Obstructive Sleep Apnea (OSA) is a prevalent health issue affecting 10-25% of adults in the United States (US) and is associated with significant economic consequences. Machine learning methods have shown promise in improving the efficiency and accessibility of OSA diagnoses, thus reducing the need for expensive and challenging tests. A comparative analysis of Logistic Regression (LR), Support Vector Machine (SVM), Gradient Boosting (GB), Gaussian Naive Bayes (GNB), Random Forest (RF), and K-Nearest Neighbors (KNN) algorithms was conducted to predict Obstructive Sleep Apnea (OSA). To improve the predictive accuracy of these models, Random Oversampling was applied to address the imbalance in the dataset, ensuring a more equitable representation of the minority class. Patient demographics, including age, sex, height, weight, BMI, neck circumference, and gender, were employed as predictive features in the models. The RFC provided outstanding training and testing accuracies of 87% and 65%, respectively, and a Receiver Operating Characteristic (ROC) score of 87%. The GBC and SVM classifiers also demonstrated good performance on the test dataset. The results of this study show that machine learning techniques may be effectively used to diagnose OSA, with the Random Forest Classifier demonstrating the best results.

Obstructive sleep apnea (OSA) is a prevalent sleep disorder that affects approximately 3–7% of males and 2–5% of females. In the United States alone, 50–70 million adults suffer from various sleep disorders. OSA is characterized by recurrent episodes of breathing cessation during sleep, thereby leading to adverse effects such as daytime sleepiness, cognitive impairment, and reduced concentration. It also contributes to an increased risk of cardiovascular conditions and adversely impacts patient overall quality of life. As a result, numerous researchers have focused on developing automated detection models to identify OSA and address these limitations effectively and accurately. This study explored the potential benefits of utilizing machine learning methods based on demographic information for diagnosing the OSA syndrome. We gathered a comprehensive dataset from the Torr Sleep Center in Corpus Christi, Texas, USA. The dataset comprises 31 features, including demographic characteristics such as race, age, sex, BMI, Epworth score, M. Friedman tongue position, snoring, and more. We devised a novel process encompassing pre-processing, data grouping, feature selection, and machine learning classification methods to achieve the research objectives. The classification methods employed in this study encompass decision tree (DT), naive Bayes (NB), k-nearest neighbor (kNN), support vector machine (SVM), linear discriminant analysis (LDA), logistic regression (LR), and subspace discriminant (Ensemble) classifiers. Through rigorous experimentation, the results indicated the superior performance of the optimized kNN and SVM classifiers for accurately classifying sleep apnea. Moreover, significant enhancements in model accuracy were observed when utilizing the selected demographic variables and employing data grouping techniques. For instance, the accuracy percentage demonstrated an approximate improvement of 4.5%, 5%, and 10% with the feature selection approach when applied to the grouped data of Caucasians, females, and individuals aged 50 or below, respectively. Furthermore, a comparison with prior studies confirmed that effective data grouping and proper feature selection yielded superior performance in OSA detection when combined with an appropriate classification method. Overall, the findings of this research highlight the importance of leveraging demographic information, employing proper feature selection techniques, and utilizing optimized classification models for accurate and efficient OSA diagnosis.