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The first (vfluc1), second (v2), and third (v3) harmonic coefficients of the azimuthal particle distribution at midrapidity are extracted for charged hadrons and studied as a function of transverse momentum (pT) and mean charged particle multiplicity density ⟨Nch⟩ in U+U (√sNN=193 GeV), Au+Au, Cu+Au, Cu+Cu, d+Au, and p+Au collisions at √sNN=200 GeV with the STAR detector. For the same ⟨Nch⟩, the vfluc1 and v3 coefficients are observed to be independent of the collision system, while v2 exhibits such a scaling only when normalized by the initial-state eccentricity (ϵ2). The data also show that ln(v2/ϵ2) scales linearly with ⟨Nch⟩−1/3. These measurements provide insight into initial-geometry fluctuations and the role of viscous hydrodynamic attenuation on vn from small to large collision systems.
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We present two-particle pt correlations as a function of event centrality for Au+Au collisions at √sNN=7.7, 11.5, 14.5, 19.6, 27, 39, 62.4, and 200 GeV at the Relativistic Heavy Ion Collider using the STAR detector. These results are compared to previous measurements from CERES at the Super Proton Synchrotron and from ALICE at the Large Hadron Collider. The data are compared with UrQMD model calculations and with a model based on a Boltzmann-Langevin approach incorporating effects from thermalization. The relative dynamical correlations for Au+Au collisions at √sNN=200 GeV show a power-law dependence on the number of participant nucleons and agree with the results for Pb+Pb collisions at √sNN=2.76TeV from ALICE. As the collision energy is lowered from √sNN=200 to 7.7 GeV, the centrality dependence of the relative dynamical correlations departs from the power-law behavior observed at the higher collision energies. In central collisions, the relative dynamical correlations increase with collision energy up to √sNN=200 GeV in contrast to previous measurements that showed little dependence on the collision energy.
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Radial velocity (RV) searches for exoplanets have surveyed many of the nearest and brightest stars for long-term velocity variations indicative of a companion body. Such surveys often detect high-amplitude velocity signatures of objects that lie outside the planetary mass regime, most commonly those of a low-mass star. Such stellar companions are frequently discarded as false-alarms to the main science goals of the survey, but high-resolution imaging techniques can be employed to either directly detect or place significant constraints on the nature of the companion object. Here, we present the discovery of a compact companion to the nearby star HD 118475. Our Anglo-Australian Telescope RV data allow the extraction of the full Keplerian orbit of the companion, which is found to have a minimum mass of 0.445 M o. Follow-up speckle imaging observations at the predicted time of maximum angular separation rule out a main-sequence star as the source of the RV signature at the 3.3σ significance level, implying that the companion must be a low-luminosity compact object, most likely a white dwarf. We provide an isochrone analysis combined with our data that constrain the possible inclinations of the binary orbit. We discuss the eccentric orbit of the companion in the context of tidal circularization timescales and show that non-circular orbit was likely inherited from the progenitor. Finally, we emphasize the need for utilizing such an observation method to further understand the demographics of white dwarf companions around nearby stars. © 2019. The American Astronomical Society. All rights reserved.
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Convolutional neural networks (CNN) are a class of machine learning model that are especially well suited for imagebased tasks. In this study, we design and train a CNN on tissue samples imaged using Multi-Photon Microscopy (MPM) and show that the model can distinguish between chromophobe renal cell carcinoma (chRCC) and oncocytoma. We demonstrate the method to train a model using simple max-pooling vote fusion, and use the model to highlight regions of the input that cause a positive classification. The model can be tuned for higher sensitivity at the cost of specificity with a constant threshold and little impact to accuracy overall. Several numerical experiments were run to measure the model’s accuracy on both image and patient level analysis. Our models were designed with a dropout parameter that biases the model towards higher sensitivity or specificity. Our best performance model, as measured by area under the receiver operating characteristic curve (AUC of ROC, or AUROC) on patient level classification, is measured with a 94% AUROC and 88% accuracy, along with 100% sensitivity and 75% specificity.
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In this study, nanoparticles of pure zinc oxide (ZnO) and ZnO doped with iron of various doping concentrations (Zn1- xFexO) are analyzed using fluorescence spectroscopy. Excitation and emission spectra using various operating wavelengths were collected. Individual spectra and excitation emission matrix were analyzed. Various peaks including strong ultraviolet (UV) emission peaks and strong blue emission peaks that are corresponding to the near-band-edge emission (NBE) and defect emission (DE) peaks were studied based on the peak intensities, peak wavelengths, and NBE peak to defect peak ratios. The Zn1-xFexO materials were also analyzed using X-ray diffraction and optical absorption spectroscopy. The variation in the band gap energy and in the NBE emission energy with dopant concentration was analyzed. A red-shift was observed with the NBE emission peak. The NBE to DE ratio initially increases from pure ZnO to Zn0.97Fe0.03O and then decreases as the dopant concentration increases.
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We present three-particle mixed-harmonic correlations 〈cos(mϕa+nϕb−(m+n)ϕc)〉 for harmonics m,n=1−3 for charged particles in sNN=200 GeV Au+Au collisions at RHIC. These measurements provide information on the three-dimensional structure of the initial collision zone and are important for constraining models of a subsequent low-viscosity quark–gluon plasma expansion phase. We investigate correlations between the first, second and third harmonics predicted as a consequence of fluctuations in the initial state. The dependence of the correlations on the pseudorapidity separation between particles show hints of a breaking of longitudinal invariance. We compare our results to a number of state-of-the art hydrodynamic calculations with different initial states and temperature dependent viscosities. These measurements provide important steps towards constraining the temperature dependent viscosity and longitudinal structure of the initial state at RHIC. © 2018 The Author
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We present the first measurement of the proton correlation function in heavy-ion collisions for the central (0–40%) and peripheral (40–80%) Au + Au collisions at sNN=200 GeV by the STAR experiment at the Relativistic Heavy-Ion Collider (RHIC). Predictions for the ratio of peripheral collisions to central collisions for the proton correlation function are sensitive to the presence of a nucleon bound state. These predictions are based on the proton interaction extracted from (2+1)-flavor lattice QCD calculations at the physical point. The measured ratio of the proton correlation function between the peripheral (small system) and central (large system) collisions is less than unity for relative momentum smaller than 40 MeV/c. Comparison of our measured correlation ratio with theoretical calculation slightly favors a proton bound system with a binding energy of ∼ 27 MeV.
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New data obtained during the 2018 March-April speckle run at the 4.1 m Southern Astrophysical Research (SOAR) telescope located at Cerro Pachón (Chile) allowed us to recalculate the orbits of the following visual binaries: WDS 06478+0020 (STT 157),WDS 07003-2207 (FIN 334Aa,Ab), WDS 07013-0906 (A 671), WDS 10174-5354 (CVN 16Aa,Ab), WDS 12155-3106 (RST 1658),WDS 12572+0818 (FIN 380),WDS 13044-1316 (HU 642),WDS 14243-3838 (RST 1785), WDS 16094-3103 (I 557), WDS 17115-1630 (HU 169), WDS 17119-0151 (LPM 629),WDS 17563 + 0259 (A 2189),WDS 18464-2755 (RST 2073), and WDS 19035-6845 (FIN 357). All but three of them are Southern stars. The recently published Gaia parallaxes were used to calculate the total mass of each of these systems, despite the fact that, in a few cases, only Hipparcos parallaxes were available. For two binaries, A 671 and RST 2073, there are no parallax data. However, in these cases, the masses deduced from the dynamical parallaxes provided relevant information. In addition, we also present the first orbit for each of three systems: HU 642, RST 1785, and RST 2073, using speckle measurements. Finally, using the dynamical parallaxes given by these orbits, we have been able to calculate the luminosity of these systems. Said luminosities allow us to indicate an approximate age for each of the components of the system, situating them within the HR diagram. © 2018 The Author(s) Published by Oxford University Press on behalf of the Royal Astronomical Society.
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We present 248 speckle observations of 43 binary and 19 trinary star systems chosen to make progress in two main areas of investigation: the fundamental properties of metal-poor stars and star formation mechanisms. The observations were taken at the Gemini North and South telescopes during the period 2015 July to 2018 April, mainly with the Differential Speckle Survey Instrument but also with a few early results from the new 'Alopeke speckle camera at Gemini North. We find that the astrometry and photometry of these observations as a whole are consistent with previous work at Gemini. We present five new visual orbits for systems important in understanding metal-poor stars, three of which have orbital periods of less than 4 yr, and we indicate the degree to which these and future observations can impact our knowledge of stellar properties and star formation. In particular, we find a decrease in mass at fixed spectral type for metal-poor stars versus their solar-metallicity analogs that is consistent with predictions that are made from current stellar models. © 2019. The American Astronomical Society. All rights reserved..
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This chapter first reviews the research and applications of nonresonance and resonance Raman spectroscopy for analysis of human brain normal and abnormal tissues. Next, special emphasis is made on our recent achievements of visible resonance Raman (VRR) technique in primary human brain tumor disease investigation and diagnosis. Visible resonance Raman (VRR) spectroscopy technique uses excitation of visible light (532 nm) to evaluate the resonant and nonresonant molecular vibrational modes in biological tissues. The VRR signal intensities are enhanced by two to three orders of magnitude for faster use in medical applications in quasi real time. VRR opens up a new stainless “molecular optics based histopathology” diagnosis approach. © 2019 Elsevier Ltd. All rights reserved.
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We explore the origins of the young B-type stars found by Casetti-Dinescu et al. (2014) at the outskirts of the Milky-Way disk in the sky region of Leading Arm of the Magellanic Stream. High-resolution spectroscopic observations made with the MIKE instrument on the Magellan Clay 6.5m telescope for nine stars are added to the previous sample analyzed by Zhang et al. (2017). We compile a sample of fifteen young stars with well-determined stellar types, ages, abundances and kinematics. With proper motions from Gaia DR2 we also derive orbits in a realistic Milky-Way potential. We find that our previous radial-velocity selected LA candidates have substantial orbital angular momentum. The substantial amount of rotational component for these stars is in contrast with the near-polar Magellanic orbit, thus rendering these stars unlikely members of the LA. There are four large orbital-energy stars in our sample. The highest orbital-energy one has an age shorter than the time to disk crossing, with a birthplace z = 2.5 kpc and R GC ~ 28 kpc. Therefore, the origin of this star is uncertain. The remaining three stars have disk runaway origin with birthplaces between 12 and 25 kpc from the Galactic center. Also, the most energetic stars are more metal poor ([Mg/H] =-0.50 +/- 0.07) and with larger He scatter (sigma [He/H] = 0.72) than the inner disk ones ([Mg/H] = 0.12 +/- 0.36, sigma [He/H] = 0.15). While the former group's abundance is compatible with that of the Large Magellanic Cloud, it could also reflect the metallicity gradient of the MW disk and their runaway status via different runaway mechanisms.
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The purpose of this study is to examine optical spatial frequency spectroscopy analysis (SFSA) combined with visible resonance Raman (VRR) spectroscopic method, for the first time, to discriminate human brain metastases of lung cancers adenocarcinoma (ADC) and squamous cell carcinoma (SCC) from normal tissues. A total of 31 label-free micrographic images of three types of brain tissues were obtained using a confocal micro-Raman spectroscopic system. VRR spectra of the corresponding samples were synchronously collected using excitation wavelength of 532[Formula: see text]nm from the same sites of the tissues. Using SFSA method, the difference in the randomness of spatial frequency structures in the micrograph images was analyzed using Gaussian function fitting. The standard deviations, [Formula: see text] calculated from the spatial frequencies of the micrograph images were then analyzed using support vector machine (SVM) classifier. The key VRR biomolecular fingerprints of carotenoids, tryptophan, amide II, lipids and proteins (methylene/methyl groups) were also analyzed using SVM classifier. All three types of brain tissues were identified with high accuracy in the two approaches with high correlation. The results show that SFSA–VRR can potentially be a dual-modal method to provide new criteria for identifying the three types of human brain tissues, which are on-site, real-time and label-free and may improve the accuracy of brain biopsy.
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In this volume, we have put together papers spanning a broad range from the area of modeling of strain and misfit dislocation densities, microwave absorption characteristics of nanocomposites, to X-ray diffraction studies. Specific topics in this volume include: Modeling of strain relaxation and defect dynamics in buffer layers for semiconductor devices fabricated on lattice-mismatched substrates, which enables technology for advanced computer chips, multi-junction solar cells, detectors, and microwave transistors. Physical Unclonable Functions (PUFs) are probabilistic circuit primitives that extract randomness from the physical characteristics of devices. One of the papers outlines PUF design based on resistor and capacitor variations for low pass filters (LoPUF). Spatial wavefunction switching (SWS) FETs, which can process 2-bits per FET using CMOS-SWS logic, thus enabling multivalued logic (MVL) and compact DRAMs. Perimeter gated single-photon avalanche diode (PGSPAD). The applied voltage at the gate terminal modulates the electric field, making it uniform throughout the junction. This gating technique is an efficient method to prevent premature edge breakdown, one of the major problems in operating avalanche photodiodes implemented in CMOS process. In summary, papers selected in this volume cover various aspects of high performance logic and circuits for high-speed electronic systems. © 2019 by World Scientific Publishing Co. Pte. Ltd. All rights reserved.
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High Entropy Alloys are inherently complex and span a vast composition space, making their research and discovery challenging. Developing quantitative predictions of their phase selection requires a large quantity of consistently determined experimental data. Here, we use combinatorial methods to fabricate and characterize 2478 quinary alloys based on Al and transition metals. All data are publicly available at http://materialsatlasproject.org/. Phase selection can be predicted for considered alloys when combining the content of FCC/BCC elements and the constituents’ atomic size difference. Mining our data reveals that High Entropy Alloys with increasing atomic size difference prefer BCC structure over FCC. This preference is typically overshadowed by other selection motifs, which dominate during close-to-equilibrium processing. Not suggested by the Hume-Rothery rules, this preference originates from the ability of the BCC structure to accommodate a large atomic size difference with lower strain energy penalty which can be practically only realized in High Entropy Alloys. © 2019 Acta Materialia Inc.
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Graphene oxide (GO)/MnO2 nanocomposites were synthesized by adding KMnO4 in a solution of water and ethanol (3:1), containing 10 mg of GO. Brown precipitates were obtained after a continuous stirring for 1 hr. The precipitates were then washed with deionized water (DI) water and dried to obtain the MnO2-GO nanocomposites. Pure MnO2 was also synthesized using the same method without GO for the comparison. X-ray diffraction pattern confirm δ-MnO2 type of MnO2 with birnessite type MnO2 structure. The TEM images show the average diameter of MnO2 nanorods as 15 nm. Electrochemical characterizations were carried out in an aqueous solution of 3M KOH. Charge-discharge studies were carried out between 1A/g to 20 A/g current range. The MnO2-GO nanocomposites showed improved electrochemical performances. The capacitance of MnO2 and MnO2-GO electrodes was found to be as 300 F/g, and 350 F/g, respectively at a current of 0.5 A/g. © 2019 Materials Research Society.
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We report results of speckle-interferometric monitoring of visual hierarchical systems using the newly commissioned instrument NN-EXPLORE Exoplanet and Stellar Speckle Imager at the 3.5 m WIYN telescope. During one year, 390 measurements of 129 resolved subsystems were made, while some targets were unresolved. Using our astrometry and archival data, we computed 36 orbits (27 for the first time). Spectro-interferometric orbits of seven pairs are determined by combining positional measurements with radial velocities measured, mostly, with the Center for Astrophysics digital speedometers. For the hierarchical systems HIP 65026 (periods 49 and 1.23 yr) and HIP 85209 (periods 34 and 1.23 yr) we determined both the inner and the outer orbits using astrometry and radial velocities and measured the mutual orbit inclinations of 11.°3 ± 1.°0 and 12.°0 ± 3.°0, respectively. Four bright stars are resolved for the first time; two of those are triple systems. Several visual subsystems announced in the literature are shown to be spurious. We note that subsystems in compact hierarchies with outer separations less than 100 au tend to have less eccentric orbits compared to wider hierarchies. © 2019. The American Astronomical Society. All rights reserved..
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The accurate identification of the human brain tumor boundary and the complete resection of the tumor are two essential factors for the removal of the glioma tumor in brain surgery. We present a visible resonance Raman (VRR) spectroscopy technique for differentiating the brain tumor margin and glioma grading. Eighty-seven VRR spectra from twenty-one human brain specimens of four types of brain tissues, including the control, glioma grade II, III, and IV tissues, were observed. This study focuses on observing the characteristics of new biomarkers and their changes in the four types of brain tissue. We found that two new RR peaks at 1129 cm-1 and 1338 cm-1 associated with molecular vibrational bonds in four types of brain tissues are significantly different in peak intensities of VRR spectra. These two resonance enhanced peaks may arise from lactic acid/phosphatidic acid and adenosine triphosphate (ATP)/nicotinamide adenine dinucleotide, respectively. We found that lactic acid and ATP concentrations vary with glioma gratings. The higher the grade of malignancy, the more the increase in lactic acid and ATP concentrations. These two RR peaks may be considered as new molecular biomarkers and used to evaluate glioma grades and identify the margin of gliomas from the control tissues. The metabolic process of lactic acid and ATP in glioma cells based on the VRR spectral changes may reveal the Warburg hypothesis. © 2018 Author(s).
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We present a measurement of inclusive J/ψ production at mid-rapidity (|y|¡1) in p+p collisions at a center-of-mass energy of s=200 GeV with the STAR experiment at the Relativistic Heavy Ion Collider (RHIC). The differential production cross section for J/ψ as a function of transverse momentum (pT) for 0¡pT¡14 GeV/c and the total cross section are reported and compared to calculations from the color evaporation model and the non-relativistic Quantum Chromodynamics model. The dependence of J/ψ relative yields in three pT intervals on charged-particle multiplicity at mid-rapidity is measured for the first time in p+p collisions at s=200 GeV and compared with that measured at s=7 TeV, PYTHIA8 and EPOS3 Monte Carlo generators, and the Percolation model prediction.
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Recent speckle observations performed at the Discovery Channel Telescope, the Gemini North Telescope, and the Special Astrophysical Observatory 6 m Telescope have permitted us to calculate the visual orbit of SB2 HD 114882 for the first time and to improve the visual orbits of two other SB2 systems, HD 30712 and HD 183255, using algorithms published by the authors of this research. Recently, new high-quality spectroscopic orbits have been obtained for these binaries by other authors. We determine their 3D orbits, individual masses, and orbital parallaxes, and present them in this paper. The parallaxes are compared with those available from the Gaia mission, and a comparison between the values confirms the precision of the results obtained here. © 2018. The American Astronomical Society. All rights reserved.
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