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Based on Visible Resonance Raman (VRR) method, we have developed a novel label-free portable VRR LRR2000 Raman analyzer with a portable fiber-optic probe and used it for the classification of human gliomas ex vivo and for the analysis of changes in tumor chemical compositions in molecular level. The purpose of this study was to examine the performance of the LRR2000 Raman analyzer as an optical biopsy tool for detecting human brain tumors compared to the commercial laboratory HR800 and WITec300 micro confocal Raman spectroscopy instruments. As of 2018, a total 1,938 VRR spectra were collected using LRR2000, HR800 and WITec300 Raman system, ex vivo. Identification of the four grades of glioma tumors and control tissues was performed based on the characteristic native molecular fingerprints. LRR2000 demonstrated consistent diagnostic results with HR800 and WITec300 Raman systems. LRR2000 showed the advantages of high speed, convenience and low cost compared to the two confocal micro Raman systems. Using artificial intelligence (AI)-based analysis of part of the data, the cross-validated accuracy for identifying glioma tumors is ~90% compared with gold standard histopathology examination.

Purpose: Without having a shared operationalization of what constitutes a direct-to-consumer advertising (DTCA) exposure, it is impossible to accurately generalize findings about their effects. First, it needs to be established how the variables involved in exposures impact outcomes. This will allow for more accurate operationalizations. Design/methodology/approach: A sample of 216 participants were recruited from Amazon’s Mechanical Turk and randomly assigned into one of four conditions to take an online survey. A 2 × 2 experiment (active/passive attention × low/high exposure) was conducted to determine if the level of attention, otherwise known as attentiveness, and the number of exposures impacted preferences for a fictitious prescription sleep aid. Findings: Results indicated a significant difference among active and passive conditions such that active exposures resulted in stronger positive preferences. Research limitations/implications: Studies using different operationalizations should not be aggregated for generalizations about the effects of DTCA of prescription drugs. Originality/value: This paper urges researchers to clearly operationalize their definitions for “exposure” and to be hesitant about generalizing findings studies using different definitions. © 2020, Emerald Publishing Limited.

Purpose: This paper addresses the current disruption in the educational status quo ante that has been caused by the worldwide outbreak of COVID-19. Its purpose is to suggest how practicing educators, their professional associations and the university-based researchers with whom they partner might capitalize on the unanticipated opportunity to impact education policy that the pandemic presents. Design/methodology/approach: The author draws upon his own preparation and experiences – first as a long-time practitioner in the elementary and secondary school setting, then as a university professor – to offer insights and suggestions to practicing educators, their professional associations and the university-based researchers with whom they partner. Findings: Despite the unexpected challenges that the COVID-19 pandemic has presented to educators – challenges to which educators around the globe have risen admirably – the current crisis also affords practicing educators, their professional associations and the university-based researchers with whom they partner to change the status quo ante for the better. Originality/value: The particular value of this piece is twofold: its analysis of the impact of this unanticipated crisis upon education by an author who has served both in the elementary/secondary setting and at the university level, and its assertion that educators must avail themselves of this once-in-a-lifetime opportunity to change the educational status quo ante for the better. © 2020, Emerald Publishing Limited.

Weaknesses in smartphone security pose a severe privacy threat to users. Currently, smartphones are secured through methods such as passwords, fingerprint scanners, and facial recognition cameras. To explore new methods and strengthen smartphone security, we developed a capacitive swipe based user authentication and identification technique. Swipe is a gesture that a user performs throughout the usage of a smartphone. Our methodology focuses on using the capacitive touchscreen to capture the user's swipe. While the user swipes, a series of capacitive frames are captured for each swipe. We developed an algorithm to process this series of capacitive frames pertaining to the swipe. While different swipes may contain different numbers of capacitive frames, our algorithm normalizes the frames by constructing the same number of frames for every swipe. After applying the algorithm, we transform the normalized frames into gray scale images. We apply principal component analysis (PCA) to these images to extract principal components, which are then used as features to authenticate/identify the user. We tested random forest (RF) and support vector machine (SVM) algorithms as classifiers. For authentication, the performance of SVM (tested with left swipes) was more promising than RF, yielding a maximum accuracy of 79.88% with an FAR and FRR of 15.84% and 50%, respectively. SVM (tested with right swipes) produced our maximum identification accuracy at 57.81% along with an FAR and FRR of 0.60% and 42.18%, respectively. © 2020 IEEE.

In the past 5 years, we have been using XSEDE resources and ECSS support to conduct research at Southern Connecticut State University (SCSU), a primary undergraduate institution (PUI). First, the regioselectivity was successfully investigated in the synthesis of 5-FU derivatives with phase transition method and silver salt method; then the Hard and Soft Acids and Bases (HSAB) principle and the Marcus theory were unified in the study of ambident reactivity; at last our research was expanded from reactions of molecules to reactions on the solid surface. We would like to share our results and emphasize the importance of XSEDE resources and ECSS support for the research in PUIs. © 2020 ACM.

Objectives: Cranial vault modification (CVM), the intentional reshaping of the head, indicated group affiliation in prehistoric Andean South America. This study aims to analyze CVM data from the Cuzco region of Peru to illuminate patterns of early migration and settlement along with the later impact of the Inca Empire (AD 1438–1532) on the ethnic landscape. Materials and Methods: 419 individuals from 10 archaeological sites spanning over 2300 years were assessed for CVM using morphological analysis. Results: CVM patterns show distinct temporal attributes: the tabular type of modification appeared first and dominated the early sample (900 BC–AD 600), followed by an influx of unmodified crania during the Middle Horizon (AD 600–1000). The annular type appeared later during the Late Intermediate Period (AD 1000–1438). In the subsequent period of Inca imperialism, modification rates were higher at sites in the Cuzco countryside than in Cuzco city sites. Discussion: The study results, combined with archaeological and ethnohistoric data, reveal the sociopolitical transformations that occurred prior to and during the rise of the Inca Empire. The influx of unmodified crania during the Middle Horizon resulted at least partly from Wari occupation, while the appearance of the annular type during the LIP points to migration into the area, possibly from the Lake Titicaca region. In the Inca Imperial Period, Inca individuals at Cuzco city sites refrained from modification as a sign of their ethnic identity, while modification patterns in the Cuzco countryside likely reflect state-coerced resettlement of different ethnic groups. © 2020 Wiley Periodicals LLC.

Using data on a sample of small Iowa towns consistently collected over two decades, we investigate how agglomeration economies, social capital, human capital, local fiscal policy, and natural amenities affect new firm entry. We find that human capital and agglomeration are more conducive to new firm entry than are natural amenities, local fiscal policy, or social capital. The impact of local fiscal policy is too small to overcome the locational disadvantages from insufficient endowment of human capital and agglomeration. A rural development approach that encourages firm entry in rural towns with the largest endowments of human capital and market agglomeration would be more successful than trying to raise firm entry in every town.

Background: Incivility and bullying within the profession of nursing remains a problem within the workplace. As a result, healthcare workplaces can become unhealthy and difficult for nurses to function within. Work productivity is impacted and patients' healthcare is placed at risk when nurses are emotionally and physically affected by workplace incivility and bullying. Clinical nurse leaders (CNLs) applying theoretical reasoning and nursing competencies' in addressing bullying and incivility within the workplace, can provide an organized and effective organizational approach to addressing bullying and incivility in work environments. Methods: Theoretical reasoning and nursing competencies in addressing bullying and incivility within the workplace, will be examined as a means to identify nurses exhibiting signs and symptoms of bullying and incivility in work environments. The theory of The Hollow will identify the origins of affected nurses' behaviors and the physiological and psychological impact of bullying and incivility. The CNL role will be used as a facilitator of change at the microsystem level. And competencies for addressing behaviors associated with bullying and incivility will be addressed. Approach: Innovation adapted from prior research and literature developed by the author, extrapolated from the literature on workplace bullying and incivility in nursing practice. Outcomes: Bullying and incivility can be resolved in the workplace when competencies are set forth by nursing leaders to educate and empower nursing staff on expectations of healthy work environments. Conclusion: Healthy workplaces are achievable when nurse leaders, such as CNLs, educate and empower nurses to have the expectation of healthy work environments not only for themselves, but for all nurses. © 2020 Wiley Periodicals LLC

BACKGROUND: Opioid overdoses are primarily discussed by the pharmacological properties of the drugs used. Research shows that other factors such as the social/physical environment and the mental/emotional states can have an impact on overdose events. Ataiants and colleagues (2020) used Zinberg's "drug, set, and setting" framework to identify circumstances surrounding overdose experiences of street-involved women in Philadelphia. The aim of this paper is to extend their analysis to a diverse sample of suburban women who experienced overdoses., METHODS: The mixed-methods design consisted of ethnographic fieldwork, in-depth interviews, and brief surveys with 32 suburban women who use opioids. Inductive theoretical reasoning and constant comparative analysis facilitated themes emerging within the "drug, set, and setting" framework., RESULTS: Eighteen out of 32 women identified "drug" as the primary factor involved in their overdose events. Major themes were an inability to identify the synthetic opioid fentanyl, lack of knowledge or control over how much to use, poly-substance use, and an insufficient understanding of risks. Eleven out of 32 women linked "set" to their overdose experiences. Themes included emotional trauma, such as death of a child, child custody issues, and mental health conditions, such as depression. Six out of 32 women associated "setting" with one of their overdose experiences. Themes were related to being with friends or partners that used, and having recently been released from treatment or incarceration., CONCLUSION: Findings show similar themes found among an urban sample, adding insight on the need for effective overdose interventions targeted for suburban populations. The opioid crisis is not confined to the cities, and neither should services aimed at addressing opioid overdose. The knowledge provided here can help policy makers support female-centered harm reduction services not only in urban areas but also in the suburbs. Copyright © 2020. Published by Elsevier B.V.

We report on new measurements of inclusive J/ψ polarization at midrapidity in p+p collisions at √s=200 GeV by the STAR experiment at the Relativistic Heavy Ion Collider. The polarization parameters, λθ, λϕ, and λθϕ, are measured as a function of transverse momentum (pT) in both the helicity and Collins-Soper (CS) reference frames within pT<10 GeV/c. Except for λθ in the CS frame at the highest measured pT, all three polarization parameters are consistent with 0 in both reference frames without any strong pT dependence. Several model calculations are compared with data, and the one using the Color Glass Condensate effective field theory coupled with nonrelativistic QCD gives the best overall description of the experimental results, even though other models cannot be ruled out due to experimental uncertainties.

The measurements of particle multiplicity distributions have generated considerable interest in understanding the fluctuations of conserved quantum numbers in the quantum chromodynamics (QCD) hadronization regime, in particular near a possible critical point and near the chemical freeze-out. Net-protons and net-kaons have been used as proxies for the net-baryon number and net-strangeness, respectively. We report the measurement of efficiency- and centrality-bin width-corrected cumulant ratios (C2/C1, C3/C2) of net-Λ distributions, in the context of both strangeness and baryon number conservation, as a function of collision energy, centrality, and rapidity. The results are for Au+Au collisions at five beam energies (√sNN=19.6, 27, 39, 62.4, and 200 GeV) recorded with the Solenoidal Tracker at RHIC (STAR). We compare our results to the Poisson and negative binomial (NBD) expectations, as well as to ultrarelativistic quantum molecular dynamics (UrQMD) and hadron resonance gas (HRG) model predictions. Both NBD and Poisson baselines agree with data within the statistical and systematic uncertainties. UrQMD describes the measured net-ΛC1 and C3 at 200 GeV reasonably well but deviates from C2, and the deviation increases as a function of collision energy. The ratios of the measured cumulants show no features of critical fluctuations. The chemical freeze-out temperatures extracted from a recent HRG calculation, which was successfully used to describe the net-proton, net-kaon, and net-charge data, indicate Λ freeze-out conditions similar to those of kaons. However, large deviations are found when comparing with temperatures obtained from net-proton fluctuations. The net-Λ cumulants show a weak but finite dependence on the rapidity coverage in the acceptance of the detector, which can be attributed to quantum number conservation.

Particle production sensitive to nonfactorizable and nonperturbative processes that contribute to the underlying event associated with a high transverse momentum (pT) jet in proton+proton collisions at √s=200 GeV is studied with the STAR detector. Each event is divided into three regions based on the azimuthal angle with respect to the highest-pT jet direction: in the leading jet direction (“Toward”), opposite to the leading jet (“Away”), and perpendicular to the leading jet (“Transverse”). In the Transverse region, the average charged particle density is found to be between 0.4 and 0.6 and the mean transverse momentum, ⟨pT⟩, between 0.5 and 0.7 GeV/c for particles with pT>0.2 GeV/c at mid-pseudorapidity (|η|<1) and jet pT>15 GeV/c. Both average particle density and ⟨pT⟩ depend weakly on the leading jet pT. Closer inspection of the Transverse region hints that contributions to the underlying event from initial- and final-state radiation are significantly smaller in these collisions than at the higher energies, up to 13 TeV, recorded at the LHC. Underlying event measurements associated with a high-pT jet will contribute to our understanding of QCD processes at hard and soft scales at RHIC energies, as well as provide constraints to modeling of underlying event dynamics.

We report systematic measurements of bulk properties of the system created in Au+Au collisions at √sNN=14.5 GeV recorded by the STAR detector at the Relativistic Heavy Ion Collider (RHIC). The transverse momentum spectra of π±, K±, and p(¯p) are studied at midrapidity (|y|<0.1) for nine centrality intervals. The centrality, transverse momentum (pT), and pseudorapidity (η) dependence of inclusive charged particle elliptic flow (v2), and rapidity-odd charged particles directed flow (v1) results near midrapidity are also presented. These measurements are compared with the published results from Au+Au collisions at other energies, and from Pb+Pb collisions at √sNN=2.76 TeV. The results at √sNN=14.5 GeV show similar behavior as established at other energies and fit well in the energy dependence trend. These results are important as the 14.5-GeV energy fills the gap in μB, which is of the order of 100 MeV, between √sNN=11.5 and 19.6 GeV. Comparisons of the data with UrQMD and AMPT models show poor agreement in general.

Economic Development in Ghana and Malaysia investigates why two countries that appeared to be at more or less the same stage of economic development at one point in time have diverged so substantially. At the time of their independence from the UK in 1957, both Ghana and Malaysia were at roughly the same stage of economic development; in fact, Ghana's real per capita income was slightly ahead of Malaysia's. Since then, Ghana's development has been sluggish, while Malaysia's economy has taken off into sustained growth and today, the real per capita income of Malaysia is about five times that of Ghana. This volume examines the pre-colonial and colonial economies of both countries, and the economic policies pursued after independence. In doing so, it aims to identify policies which might have contributed to Malaysia's development and those which might have slowed Ghana's. The authors ask whether lessons can be learned from the successes of countries such as Malaysia. This detailed comparative analysis will be useful to students and researchers of development economics as well as public policy makers in developing countries. It is written in language which makes it accessible to the general reader. © 2020 Samuel K. Andoh, Bernice J. deGannes Scott and Grace Ofori-Abebrese. All rights reserved.

As a fully aquatic mammal, the Florida manatee (Trichechus manatus latirostris) spends a limited amount of time at the water's surface. However, as a mammal that breathes air, they do need to filter, warm, and humidify that air, and anecdotal evidence indicates manatees have a sense of smell. This study characterized the nasal turbinate system, including identification of the olfactory epithelium, and compared it to other mammals using a combination of gross and micro-anatomic examination. Major turbinates were present, including nasal, maxillary, and ethmoturbinates, but with minimal convolution. The respiratory epithelium was found throughout much of the nasal cavity and covered maxillary and nasal turbinates, as well as the septum. Mucus-producing cells and cavernous veins were extensive. The olfactory epithelium was found in the dorsocaudal ethmoturbinates. As a herbivore that feeds predominantly underwater, the manatee likely relies on taste and touch for assessing food and, therefore, does not need to use smell in the same way as other marine mammals such as mysticetes (Bouchard et al., 2019) and pinnipeds (Kowalewsky et al., 2006). However, there are still substantial numbers of olfactory cells, especially considering the decreased amount of exposure time to odorants when breathing at the surface. Therefore, the question remains of why manatees have maintained their ability to smell while other fully aquatic species such as odontocetes have not. Future research should focus on a combination of behavioral and molecular techniques to fully understand the olfactory capabilities of the Florida manatee. © 2020, European Association for Aquatic Mammals.

Competitive teamsport at university level is predominantly segregated by gender in many western countries, despite concerns that gender segregation in sport can perpetuate sexism and gender inequality. While policies and activities seek to challenge sexism and gender inequality, the use of gender collaboration within a gender-segregated system as a method to achieve this has received little attention. In this article, we draw on a year-long ethnography of elite sport and 48 in-depth interviews with elite male and female athletes at a British university to explore the impact of various forms of gender mixing during training, which we call ‘gender-collaborative training’. While men’s and women’s teams competing against each other in practice matches resulted in gender-essentialist narratives attributing difference to biology, gender-integrated practices and workouts provided opportunities for men and women to train together without the gendered sport-specific associations that can reproduce sexism. We call for gender-collaborative training to be adopted by gender-segregated teams, and suggest that where there is resistance to any integration, teams start with mixed physical workouts and progress to mixed sport-specific training and then mixed competitive training. © The Author(s) 2020.

Two northeast nursing schools piloted an innovative curriculum to teach The Conversation Project (TCP) to the next generation of nurses. The goal was to educate 26 graduate nursing students about how to have end-of-life and advance care planning conversations with people before they experience a crisis. The focus of assignments was on communicating newly learned TCP information. Postreflections demonstrated that participants felt their communication skills had been enhanced while their anxieties were reduced. The students' abilities to have end-of-life conversations increased. © Lippincott Williams & Wilkins.

Alexander Josiassen (2011) initiated research on the consumer disidentification (CDI). More specifically, in his investigation of 2nd generation Turks in the Netherlands, he introduced the concept of acculturation as an antecedent to consumer disidentification among this ethnic group. Josiassen's study showed that acculturation negatively affects CDI. The present replication research among American 2nd generation US immigrants confirmed Josiassen’s findings with respect to CDI. It also confirmed his findings that acculturation positively affects consumer ethnocentrism (CET). In elaborating his model, the US study found that (a) national disidentification (NDI) is inversely predictive of acculturation, and (b) acculturation is negatively predictive of consumer xenocentrism (XEN). Replication of the Netherland CDI model in the U.S. results in an acceptable measurement fit and structural fit. © 2020, University of South Australia. All rights reserved.