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Worldwide breast cancer incidence has increased by more than twenty percent in the past decade. It is also known that in that time, mortality due to the affliction has increased by fourteen percent. Using optical-based diagnostic techniques, such as Raman spectroscopy, has been explored in order to increase diagnostic accuracy in a more objective way along with significantly decreasing diagnostic wait-times. In this study, Raman spectroscopy with 532-nm excitation was used in order to incite resonance effects to enhance Stokes Raman scattering from unique biomolecular vibrational modes. Seventy-two Raman spectra (41 cancerous, 31 normal) were collected from nine breast tissue samples by performing a ten-spectra average using a 500-ms acquisition time at each acquisition location. The raw spectral data was subsequently prepared for analysis with background correction and normalization. The spectral data in the Raman Shift range of 750- 2000 cm-1 was used for analysis since the detector has highest sensitivity around in this range. The matrix decomposition technique nonnegative matrix factorization (NMF) was then performed on this processed data. The resulting leave-oneout cross-validation using two selective feature components resulted in sensitivity, specificity and accuracy of 92.6%, 100% and 96.0% respectively. The performance of NMF was also compared to that using principal component analysis (PCA), and NMF was shown be to be superior to PCA in this study. This study shows that coupling the resonance Raman spectroscopy technique with subsequent NMF decomposition method shows potential for high characterization accuracy in breast cancer detection.

The Sarbanes Oxley Act of 2002 (SOX) is documented to curb executive risk-taking and firm risk. Utilizing SOX as an exogenous shock on firm risk, we find that proxy fight threats are positively related to a firm’s total risk and idiosyncratic risk. Specifically, although firm risk generally decreases post-SOX, high proxy fight threats mitigate this change in firm risk. We also find that although firms adopt more conservative policies such as decreasing their leverage and payout post-SOX, these changes are mitigated by proxy fight threats. In sum, our findings indicate that proxy fights act as an external disciplinary mechanism, encourage executive risk-taking, and increase firm risk.

ACSM’S Exercise Testing and Prescription adapts and expands upon the assessment and exercise prescription-related content from ACSM’s Resource Manual for Guidelines for Exercise Testing and Prescription, 7th Edition, to create a true classroom resource. Fully aligned with the latest edition of ACSM’s flagship title, ACSM’s Guidelines for Exercise Testing and Prescription , this practical resource walks students through the process of selecting and administering fitness assessments, using Guidelines to interpret results, and drafting an exercise prescription that is in line with Guidelines parameters .Designed for today’s learners, the text is written in a clear, concise style, and enriched by visuals that promote student engagement. As an American College of Sports Medicine publication, the book offers the unsurpassed quality and excellence that has become synonymous with titles by the leading exercise science organization in the world.The nuances of fitness assessment and the particulars of crafting exercise prescriptions are explored in expansive sections throughout the book.A full section devoted to Special Populations prepares students to meet the needs of the full range of both typically healthy and special needs clients they’ll see in practice.Comprehensive case studies written by experts to reinforce practical applications of concepts.A wide range of online resources includes laboratory materials and activities that provide opportunities for hands-on learning, and a library of journal articles that helps students connect research to practice.100% alignment with the most up-to-date version of the ACSM’s Guidelines for Exercise Testing and Prescription enhances the learning experience, making it easy to go back and forth between Guidelines and the text.eBook available. Fast, smart, and convenient, today’s eBooks can transform learning. These interactive, fully searchable tools offer 24/7 access on multiple devices, the ability to highlight and share notes, and much more.

ACSM’S Exercise Testing and Prescription adapts and expands upon the assessment and exercise prescription-related content from ACSM’s Resource Manual for Guidelines for Exercise Testing and Prescription, 7th Edition, to create a true classroom resource. Fully aligned with the latest edition of ACSM’s flagship title, ACSM’s Guidelines for Exercise Testing and Prescription , this practical resource walks students through the process of selecting and administering fitness assessments, using Guidelines to interpret results, and drafting an exercise prescription that is in line with Guidelines parameters .Designed for today’s learners, the text is written in a clear, concise style, and enriched by visuals that promote student engagement. As an American College of Sports Medicine publication, the book offers the unsurpassed quality and excellence that has become synonymous with titles by the leading exercise science organization in the world.The nuances of fitness assessment and the particulars of crafting exercise prescriptions are explored in expansive sections throughout the book.A full section devoted to Special Populations prepares students to meet the needs of the full range of both typically healthy and special needs clients they’ll see in practice.Comprehensive case studies written by experts to reinforce practical applications of concepts.A wide range of online resources includes laboratory materials and activities that provide opportunities for hands-on learning, and a library of journal articles that helps students connect research to practice.100% alignment with the most up-to-date version of the ACSM’s Guidelines for Exercise Testing and Prescription enhances the learning experience, making it easy to go back and forth between Guidelines and the text.eBook available. Fast, smart, and convenient, today’s eBooks can transform learning. These interactive, fully searchable tools offer 24/7 access on multiple devices, the ability to highlight and share notes, and much more.

Boron compounds have been used extensively in organic synthesis for more than sixty years. Some of the best known reactions in synthesis, such as the Suzuki-Miyaura cross-coupling and the hydroboration reaction, involve boron compounds. Several natural products containing boron have been isolated in the last fifty years, including ionophoric macrodiolide antibiotics boromycin, borophycin, aplasmomycins A, B, and C, and tartrolons B, C, and E, as well as autoinducer-2. The study of compounds containing boronic acids for application in pharmaceuticals and materials science has grown tremendously over the last few decades. These include bortezomib, ixazomib, and tavaborole. Several more boron-based drugs are currently in clinical trials. Boron neutron capture therapy has the potential to provide a treatment for various cancers. In addition, materials bearing boronic acids are been studied as potential sensors for biological molecules, such as saccharides and glycoproteins that possess cis-1,2- or cis-1,3-diols.

We report the first measurements of transverse single-spin asymmetries for inclusive jet and jet+π± production at midrapidity from transversely polarized proton-proton collisions at √s=500 GeV. The data were collected in 2011 with the STAR detector sampled from 23 pb−1 integrated luminosity with an average beam polarization of 53%. Asymmetries are reported for jets with transverse momenta 6<pT<55 GeV/c and pseudorapidity |η|<1. Presented are measurements of the inclusive-jet azimuthal transverse single-spin asymmetry, sensitive to twist-3 initial-state quark-gluon correlators; the Collins asymmetry, sensitive to quark transversity coupled to the polarized Collins fragmentation function; and the first measurement of the “Collins-like” asymmetry, sensitive to linearly polarized gluons. Within the present statistical precision, inclusive-jet and Collins-like asymmetries are small, with the latter allowing the first experimental constraints on gluon linear polarization in a polarized proton. At higher values of jet transverse momenta, we observe the first nonzero Collins asymmetries in polarized-proton collisions, with a statistical significance of greater than 5σ. The results span a range of x similar to results from semi-inclusive deep-inelastic scattering but at much higher Q2. The Collins results enable tests of universality and factorization breaking in the transverse momentum-dependent formulation of perturbative quantum chromodynamics.

There can be no doubt that mobile technologies are here to stay. Global mobile traffic grew 74 percent in 2015 alone, with 563 million devices and connections added -- most of them tablets and Smartphones. This growth has been 4000-fold in the past 10 years and 400 million-fold in the past 15 years (Cisco, 2016). Mobile technologies permeate the lives of 21st century citizens as mainstays of organizational and institutional day-to-day operations, commerce, and communication and as tools used to support individuals' personal, social, and career responsibilities. In both the corporate and educational worlds, e- and m-learning and marketing with mobile technologies are moving forward at breakneck speed with, in many cases, a blurring of traditional sector boundaries. As neither the technology nor the uses are static, exploring practices and policies that underpin this quickly shifting mobile technology context is crucial for ensuring its intelligent, purposeful, and equitable use. This edited book provides a venue for researchers to share their work on mobile learning with a focus on uses for mobiles in informal settings and PK-20 classrooms, language learning, mobile gaming, leadership and policy issues, and what mobile learning in the future may be. It assists researchers and educators to consider and answer questions such as: What is "mobilelearning" today How can mobiles be used to enable learning How is mobile learning crossing or connecting economic, social, and/or cultural sectors How do specific cultural practices with media influence mobile learning (e.g

Workplace incivility remains a problem within the nursing profession. As nurse leaders, we must recognize and not ignore the complexity of cultures that have adapted incivility into the work environment. Nursing education is a discipline that requires collaborative team work, independent drive, and commitment. New nursing faculty experiencing incivility can use mindfulness-based meditation approaches to cope with uncivil behaviors experienced within the workplace. Nurse educators applying the concepts of mindfulness can learn how to provide themselves self-care by reducing stress, as enhanced daily awareness of peace and calm are incorporated into their lifestyle. Mindfulness provides a realization that control can only be given to other persons when an individual allows or accepts another's negative behaviors. Awareness of the value and importance of oneself can assist the nurse educator experiencing incivility to maintain his or her emotional, physical, and spiritual health despite the volatility of the work environment.

In this research we demonstrate how various facets of communication influence customer loyalty in a B2B selling environment. Palmatier, Scheer, and Steenkamp (2007) show that salesperson owned loyalty (customers' loyalty specific to the salesperson) can be differentiated from customers' overall loyalty to the firm. We demonstrate how various facets of communication differentially influence salesperson owned loyalty and loyalty to the firm. We find that greater bidirectional flow of communication enhances both salesperson owned loyalty and customers' loyalty to firm. However, greater frequency of communication enhances only salesperson owned loyalty. Formality in communication negatively influences salesperson owned loyalty and positively influence customers' loyalty to firm. In addition, we find an interesting moderation effect of these relationships by customers' self-construal. Theoretical and practical implications of our findings are discussed.

Background: According to the Healthy People 2020 goals, the sustainability of breastfeeding duration rates within the United States has not been achieved. To increase these rates, it is important that women with breastfeeding difficulties receive the support needed to continue breastfeeding. When supplementation occurs, it is essential that the breastfeeding relationship be preserved. Various methods of supplementation are often recommended including use of the supplemental feeding tube device (SFTD). Purpose: The question guiding this brief is “What evidence exists to support the use of an SFTD as a method of supplementation for breastfed infants?” Search Strategy: The PubMed and CINAHL databases were queried for original research published in English from 1990 through July 2016. Search terms included “supplemental feeding tube,” “breastfeeding,” “term infants,” “premature infants,” “Supplemental Nursing System,” “Lact-aid,” and “supply line.” Findings: Very limited research exists on the use of SFTDs as a method of supplementation for breastfed infants; however, existing research suggests that an SFTD may be useful as a supplementation method for breastfed infants. High-quality research is needed to evaluate the efficacy of using an SFTD for supporting exclusive and all breastfeeding rates. Implications for Practice: Nurses and providers need to be educated and trained in the use of SFTDs as well as all supplemental feeding methods. Information on efficacy and SFTD use should also be included in policies related to breastfeeding and human milk use. Implications for Research: Further research should determine best methods of supplementation for breastfed infants and should examine differences in breastfeeding rates when using the SFTD for supplementation.

Transforming the way thousands of professional school counselors approach their work with students Transforming the School Counseling Profession demonstrates how to effectively implement systemic, data-driven school counseling programs.This clearly written text presents the profession in easy-to-understand language, and is illustrated with numerous applied examples, case studies, and vignettes. The 5th Edition has been updated to include all of the latest CACREP, ASCA, and ACA standards. It also now includes the DSM-5. Coverage of cultural competence has been expanded throughout the book. Also available with MyLab Counseling MyLab is the teaching and learning platform that empowers you to reach every student. By combining trusted author content with digital tools and a flexible platform, MyLab personalizes the learning experience and improves results for each student. MyLab Counseling organizes all assignments around essential learning outcomes and the CACREP standards–enabling easy course alignment and reporting. Note: You are purchasing a standalone product; MyLab Counseling does not come packaged with this content. Students, if interested in purchasing this title with MyLab Counseling, ask your instructor to confirm the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information. If you would like to purchase both the physical text and MyLab Counseling, search for: 0134669843 / 9780134669847 Transforming the School Counseling Profession plus MyLab Counseling with Enhanced Pearson eText -- Access Card Package Package consists of:       0134610598 / 9780134610597 Transforming the School Counseling Profession 0134642651 / 9780134642659 MyLab Counseling with Enhanced Pearson eText -- Access Card -- for Transforming the School Counseling Profession

We have measured the absolute proper motion of the Sextans dwarf spheroidal galaxy using Subaru Suprime-Cam images taken at three epochs, with a time baseline of ~10 yr. We astrometrically calibrate each epoch by constructing distortion-correction 'maps' from the best available Subaru Suprime-Cam dithered data sets and from Gaia Data Release 1 positions. The magnitude limit of the proper motion study is V ~ 24. The area covered is 26.7 × 23.3 arcmin2, which is still within the core radius of Sextans. The derived proper motion is (μα, μδ) = (-0.409 ± 0.050, -0.047 ± 0.058) mas yr-1. The direction of motion is perpendicular to the major axis of the galaxy. Our measurement, combined with radial velocity and distance from the literature, implies a low eccentricity orbit, with a moderate inclination to the Galactic plane, and a period of 3 Gyr. Sextans is now some 0.4 Gyr away from its pericentre (rperi ~ 75 kpc), moving towards its apocentre (rapo ~ 132 kpc). Its orbit is inconsistent with membership to the vast polar structure of Galactic satellites. © 2018 The Author(s).

Rapid advances in neural imaging, particularly in regard to neural plasticity and brain changes, have resulted in an evolving neurorehabilitation paradigm for aphasia and related language disorders. Aphasia and Related Neurogenic Language Disorders has been adopted worldwide as a text for aphasia courses. This new 5th edition by Leonard LaPointe and Julie Stierwalt encompasses state-of-the-art concepts and approaches from an impressive cadre of experts who work in research labs, classrooms, clinics, and hospitals-including the world-renowned Mayo Clinic.As in previous editions, this book embraces a humanistic approach to treatment, addressing multicultural and multilinguistic considerations and social model interventions. The text encompasses a full continuum of cognitive-language disorder management-from everyday practicalities, assessment, and treatment to disorder-specific cases with evidence-based data. Additions to the 5th edition include chapters on pragmatics and discourse, telepractice, digital and electronic advances, funding and reimbursement, and comprehension, syntax, and linguistic based disorders.Key Features:A new chapter on neuroanatomical basics features exquisite illustrationsAn in-depth look at neurogenic communication disorders from Mayo Clinic provides firsthand insights on treating patients in an acute care hospital settingDiscussion and test questions, case studies, and clinical pearls offer invaluable didactic guidanceA chapter on expanded traumatic brain injury covers blast injuries and multisystem injuriesThis is the most comprehensive yet concise resource on aphasia and related disorders available today. New legions of speech language pathology students, residents, course directors, and practitioners will discover a remarkable guide on the treatment of communication disorders.

Edith Richman Stolzenberg (1913–2004) was the first woman to be hired as a social worker in Hartford Public High School in Hartford, Connecticut. In a career that spanned 60 years and much of 20th-century social welfare history, she was motivated by the social justice tradition of her Jewish upbringing and the religious value of hospitality to advocate for children and families. As we enter a harsh new era for social services, this oral history explores the radical possibilities for integrating social work goals and religious values.

The complexity of the human body is such that any disturbances to its homeostatic state, unreversed, can lead to the development of illness or disease. When one considers the terminology of incivility as a concept, one does not automatically equate this concept with disease or illness. However, incivility left to persist in work environments can prove mentally and physically damaging to the victim. Mindfulness can be used as a means to help nurses experiencing workplace incivility, to begin the process of emotional and physical healing.

Urban forests can serve as valuable oases for birds and other wildlife in densely-populated urban and suburban areas with proper management. This study analyzes forest health and habitat availability of a publically-owned urban forest in West Haven, Connecticut. During the first half of the twentieth-century, this urban forest was privately-owned and primarily managed as an orchard and meadow for grazing horses. By the mid-twentieth-century, farming dwindled on the land and vegetation overtook the property. Today, this closed-canopy forest, with access to both freshwater streams and marshlands, provides habitat to a variety of native and invasive plant and animal species. By identifying the forest species and characteristics of the six hectare Cove River Historic Site (CRHS) urban forest, this study serves as the first forest inventory and provides a baseline dataset to help manage an ecologically important urban forest. Additionally, we identified bird habitat opportunities and bird species at the property. This study considers both the historic land management practices of this site in tandem with present-day forest health and animal activity to understand how this fragmented forest contributes to local biodiversity. The results indicate that this property, located within the urban environment of the central Connecticut coastline, offers varied habitats and food sources for many resident and migratory bird species, as well as wildlife including foxes.

Bullying in the workplace is considered a growing epidemic and organizations are struggling to ensure appropriate responses and protocol as there is currently no individual statutory remedy. This paper provides a synthesis of current research regarding workplace bullying, legal policies, efforts to promote remedial legislation and organizational responsibility and outcomes. Workplace bullying is addressed from several perspectives including organizational consequences, characteristics of both victims and perpetrators, the current state of legislation and best practices for organizational policy. The paper also provides a discussion of developing issues related to increased technology and social media usage.