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BACKGROUND: Growing evidence supports the superior benefits of exposure to mother's own milk (MOM) in reducing prematurity-related comorbidities. Neonatal exposure to donor human Milk (DHM) is a suitable alternative when MOM is insufficient or unavailable. However, the same protective composition and bioactivity in MOM are not present in DHM. Additional evidence is needed to justify and inform evidence-based practices increasing MOM provision while optimizing adequate use of DHM for premature infants. PURPOSE: A systematic review of the literature was conducted to determine differences in neonatal outcomes among premature infants exposed to predominately MOM versus DHM. METHODS/SEARCH STRATEGY: Databases including PubMed, CINAHL and Cochrane were searched (2020-2021) using the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analysis) guidelines. Evidence was classified using the John Hopkins evidence-based practice levels and quality of evidence. RESULTS: Eleven studies met inclusion criteria. Studied neonatal outcomes included ( a ) growth parameters (n = 8), ( b ) neonatal morbidities (n = 6), and ( c ) gut microbiome (n = 4). Overall, evidence suggests DHM exposure is beneficial but not equivalent to MOM feeding. Compared with DHM, greater doses of MOM are ideal to enhance protection primarily related to infant growth, as well as gut microbiome diversity and richness. IMPLICATIONS FOR PRACTICE: Standardized and evidence-based practices are needed to clearly delineate optimal use of DHM without undermining maternal and neonatal staff efforts to support and promote provision of MOM. IMPLICATIONS FOR RESEARCH: Additional evidence from high-quality studies should further examine differences in neonatal outcomes among infants exposed to predominately MOM or DHM in settings using standardized and evidence-based feeding practices.
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The study aims to suggest a model for attitudes towards inclusive education that will yield a good fit across different countries. Moreover, we aim to explore the effect of years of teaching experience, educational work level of teachers, and the highest degree completed by teachers on teachers’ attitudes towards inclusion across different countries. A demographic scale and the ATTAS-mm were applied to 908 teachers employed in schools of general education or who offered parallel support and/or resources in five different countries (Greece, the UK, the USA, Malaysia, and Turkey). CFA suggested a 4-factor solution, which included the cognitive, affective, and behavioral factors that have been previously introduced by Gregory and Noto (2012), and a fourth factor, labeled overall attitudes towards teaching all students. In the cognitive factor, the UK had the most positive attitudes. TU, MA, and GR enrolled in the same cluster, and the USA had the least positive attitudes. In the affective factor, GR had the most positive attitude. MA and the USA enrolled in the same cluster and TU and the UK had the least positive attitudes. A similar pattern is observed for the behavioral factor with GR having the most positive attitude. TU and MA enrolled in the same cluster, and the USA and the UK had the least positive attitudes. Finally, years of teaching experience, educational work level, and the highest degree completed have a significant effect on teachers’ attitudes towards inclusion in all countries. Providing feedback for future research is the focal point of the discussion part. © 2022, Associação Brasileira de Psicologia.
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A multi-stage biometric verification system serially activates its verifiers and improves performance-cost trade-off by allowing users to submit a subset of the available biometrics. In the heart of a verifier in multi-stage systems lies the concept of ‘reject option’ where a reject region is used to identify a bad quality test sample. If the match-score falls inside the reject region, no binary (genuine/impostor) decision is made in the current stage and the verifier in the next stage is activated. Recent studies have demonstrated a significant promise of the ‘symmetric rejection method’ in choosing a suitable reject region for multi-stage verification systems. In this paper, we delve into the symmetric rejection method to gain more insights into its error reduction capabilities. Specifically, we develop a theory which mathematically proves that the symmetric rejection method reduces the false accept rate and false reject rate. Then, we empirically validate our theory. Results show that the symmetric rejection method significantly reduces the error rates, both the false accept rate and false reject rate. © 2022, The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.
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Two-particle correlation measurements projected onto two-dimensional, transverse rapidity coordinates (yT1,yT2) provide an independent, orthogonal view of the multidimensional correlation distribution that is most often studied via angular projections. As such, these independent transverse projections allow access to manifestations of dynamical fluctuations in relativistic heavy-ion collisions that angular-correlation measurements may not be sensitive to. We report nonidentified charged-particle correlations for Au+Au minimum-bias collisions at √sNN=200 GeV taken by the STAR experiment at the Relativistic Heavy-Ion Collider (RHIC). Correlations are presented as two-dimensional functions of transverse rapidity for like-sign, unlike-sign, and all charged-particle pairs, as well as for particle pairs whose relative azimuthal angles lie on the near-side, the away-side, or at all relative azimuth. The correlations are constructed using charged particles with transverse momentum pT≥0.15 GeV/c, pseudorapidity from −1 to 1, and azimuthal angles from −π to π. The significant correlation structures that are observed evolve smoothly with collision centrality. The major correlation features include a saddle shape plus a broad peak with maximum near yT≈3, corresponding to pT≈1.5 GeV/c. The broad peak is observed in both like- and unlike-sign charge combinations and in near- and away-side relative azimuthal angles. The all-charge, all-azimuth correlation measurements are compared with the predictions of hijing and epos to provide theoretical context for these new measurements. The results indicate that the correlations for peripheral to mid-central collisions can be approximately described as a superposition of nucleon + nucleon collisions with minimal effects from the quantum chromodynamics medium. Strong medium effects are indicated in mid- to most-central collisions.
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The STAR Collaboration reports measurements of the transverse single-spin asymmetries, AN, for inclusive jets and identified “hadrons within jets” production at midrapidity from transversely polarized pp collisions at √s=200 GeV, based on data recorded in 2012 and 2015. The inclusive jet asymmetry measurements include AN for inclusive jets and AN for jets containing a charged pion carrying a momentum fraction z>0.3 of the jet momentum. The identified hadron within jet asymmetry measurements include the Collins effect for charged pions, kaons, and protons, and the Collins-like effect for charged pions. The measured asymmetries are determined for several distinct kinematic regions characterized by the jet transverse momentum pT and pseudorapidity η, as well as the hadron momentum fraction z and momentum transverse to the jet axis jT. These results probe higher momentum scales (Q2 up to ∼900 GeV2) than current, semi-inclusive deep-inelastic scattering measurements, and they provide new constraints on quark transversity in the proton and enable tests of evolution, universality, and factorization breaking in the transverse-momentum-dependent formalism.
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Objectives The present study investigated the comprehension of subject and object who and which questions in children with cochlear implants (CI).Methods Growth Curve Analysis (GCA) was used to compare eye gaze fixations and gaze patterns to the appropriate subject or object nouns within a four-picture array between 16 children with CI and 31 children with typical hearing (aged 7;0-12;0) on wh-questions with and without added adjectives to increase length. Offline accuracy was also compared.Results Findings indicated children with typical hearing exhibited more fixations to the target noun across all conditions, supporting higher comprehension accuracy. Both groups of children demonstrated more fixations to the target noun in object questions and questions without added length. Patterns of eye movement were significantly different between groups, suggesting different patterns of eye gaze across the array before fixation on the target noun. Children with CI exhibited fewer fixations, slower speed to fixation, and differences in gaze patterns that may imply the presence of processing limitations. Error analyses also suggested that children with CI frequently fixated on a picture similar to the target noun.Conclusions Results indicate children with CI comprehend questions more slowly than their hearing peers, which may be related to limitations in working memory.
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While the ocean space has long been ignored by social sciences, the past 15 years have witnessed an increased interest in the marine environment by scholars in Human Geography. The academic literature on the blue economy, almost non-existent a few years ago, is now burgeoning. The academic debate has offered some critical assessment of blue economy initiatives, but more needs to be done to address the true place of environmental protection within a blue economy, and to put people at the centre of concerns and analyses. Of particular concern, is the ambiguity of the blue economy concept and the confusion over its social and environmental sustainability, which can ultimately result in harmful practices. An important question is then how should social scientists in general and geographers, specifically, engage with these debates, and in particular how should the potential human and social costs of the blue economy be investigated and addressed while assuring justice and fairness? The papers presented here share the vision that environmental sustainability, justice and equality should be at the heart of the blue economy; not just conceptually, but practically too. The papers pursue efforts to identify blue economy risks and the mechanisms through which they occur; assess the place of inclusion and participation in a sustainable blue economy; define what blue economy policies should include to drive just and sustainable practices; and identify where the dominant understandings of the blue economy and its priorities are coming from. In other words, they put considerations of justice and broader cultural structures at the centre of their concerns and analysis. They also highlight the need to bypass geographical boundaries and gain insights from other disciplines and methodologies to grasp such an encompassing concept, and foster not just a blue economy with social justice, but a blue economy for social justice.
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Objective: We examined students’ perceptions and opinions regarding others’ COVID-19 mitigation behaviors and how these behaviors impacted feelings of safety and desire for on-campus engagement. Participants: Undergraduate and graduate students enrolled at a midsize regional state university during the Spring 2021 semester (n = 893). Methods: A cross-sectional survey design was utilized with an online and anonymous questionnaire. Scale means were calculated followed by ANOVAs to determine significance. Results: Two independent variables impacted students’ feelings of safety for on-ground courses and activities: living situation (on campus, with roommates) and school year (freshman/sophomores). Underclassmen were more likely to desire in-person campus engagement. Conclusions: Students showed a willingness to return to campus, but also concern over peer behaviors and remaining safe. Returning to a pre-pandemic social environment is critical for students’ mental health, and making students feel safe on campus is an important first step to return campuses to vibrant educational and social communities.
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Many schools of social work around the United States of America wrote anti-racism statements because of the recent murders of Black and Brown people. In this contribution, the authors describe a challenging and tense discussion of racism and anti-racism leading to a group process about oppression and anti-oppression in the social work profession. For some, the urgency to address racism led to tactics and strategies that got in the way of social workers engaging in anti-oppressive practices. While the structure of higher education often reinforces traditional hierarchies of power, the profession of social work calls us to promote our core values of social justice, integrity, and the importance of human relationships as we strive for an anti-oppressive future. Consequently, social work faculty may experience role conflict as we navigate these tensions. We believe it is important to harness and process such discomfort as we critically examine the power dynamics within our own department, and our own profession. This voluntary, ad hoc group, composed of a diverse group of faculty members, provides space for ongoing mutual aid, consciousness raising, appropriate discomfort, and accountability. If anti-racism is the goal, then anti-oppression is how we get there.
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INTRODUCTION: Adult sea lamprey (Petromyzon marinus) cease feeding and migrate to spawning streams where males build nests, undergo final sexual maturation, and subsequently produce and release large quantities of bile acid pheromones that attract mature females. These animals are predicted to rearrange their metabolic pathways drastically to support their reproductive strategies, presenting advantageous opportunities to examine how sex and the maturation processes affect metabolism. OBJECTIVES: The objective is to investigate the metabolic differences between sexes and maturation states in sea lamprey that support changes in physiological functions. METHODS: We compared plasma metabolomes of spawning and prespawning sea lamprey in both sexes using both non-targeted and targeted metabolomics approaches using UPLC/MS-MS with electrospray ionization in both positive and negative modes. The data were processed using Progenesis QI, Compound Discoverer and XCMS softwares for alignment, peak picking, and deconvolution of the peaks. Principle component analyses (PCA) and partial least squares discriminant analyses (PLS-DA) were performed using SIMCA and Metaboanalyst softwares to identify discriminating features, followed by fragmentation matching with extensive database search and pathway mapping. RESULTS: The pheromonal bile acid biosynthesis was upregulated significantly in males compared to females. Spermiating males further upregulated bile acid biosynthesis by altering amino acid metabolisms, upregulating cofactors and nucleotide metabolisms, but downregulating carbohydrate and energy metabolisms. CONCLUSION: Plasma metabolomes are sex- and maturation-dependent and reflect the special metabolic demands at each life stage and reproductive strategy.
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Obstructive sleep apnea syndrome (OSAS) is a pervasive disorder with an incidence estimated at 5–14 percent among adults aged 30–70 years. It carries significant morbidity and mortality risk from cardiovascular disease, including ischemic heart disease, atrial fibrillation, and cerebrovascular disease, and risks related to excessive daytime sleepiness. The gold standard for diagnosis of OSAS is the polysomnography (PSG) test which requires overnight evaluation in a sleep laboratory and expensive infrastructure, which renders it unsuitable for mass screening and diagnosis. Alternatives such as home sleep testing need patients to wear diagnostic instruments overnight, but accuracy continues to be suboptimal while access continues to be a barrier for many. Hence, there is a continued significant underdiagnosis and under-recognition of sleep apnea in the community, with at least one study suggesting that 80–90% of middle-aged adults with moderate to severe sleep apnea remain undiagnosed. Recently, we have seen a surge in applications of artificial intelligence and neural networks in healthcare diagnostics. Several studies have attempted to examine its application in the diagnosis of OSAS. Signals included in data analytics include Electrocardiogram (ECG), photo-pletysmography (PPG), peripheral oxygen saturation (SpO2), and audio signals. A different approach is to study the application of machine learning to use demographic and standard clinical variables and physical findings to try and synthesize predictive models with high accuracy in assisting in the triage of high-risk patients for sleep testing. The current paper will review this latter approach and identify knowledge gaps that may serve as potential avenues for future research.
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Thousands of people living with HIV are incarcerated in the United States. Research about this vulnerable community has focused on access and adherence to medical care, including the impact of stigma on these treatment outcomes. This study presents qualitative data collected from 18 incarcerated and formerly incarcerated men and women living with HIV to expand knowledge about how HIV stigma shapes the lived experience of incarceration. The HIV Stigma Framework, including theory about enacted, anticipated, and internalized stigma, was used to analyze participants’ narratives. Findings demonstrate an ongoing struggle with all three of these stigma mechanisms. Most participants deliberately concealed their HIV status and, therefore, experienced little enacted stigma. However, their narratives do describe anticipated stigma and, to a lesser extent, internalized stigma. There were gender differences in HIV disclosure and symbolic stigma and intersectionality are used to understand this variation. These findings illustrate the persistence of HIV stigma in correctional institutions and underscore the importance of fighting HIV stigma and homophobia within social work practice.
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In addition to traumas that heterosexual and cisgender people experience, queer and transgender people face a heterosexist and cissexist culture, in which marginalization and trauma against them is normalized or minimized. In this chapter, the experience of hate crimes and violence, relational and interpersonal trauma, religious based-trauma, and sociocultural and political-based trauma are covered in relation to how it impacts Lesbian, Gay, Bisexual, Trans, and Queer (LGBTQ) people. Clinical and counseling implications are discussed. The increase in mental health challenges is explained via the minority stress model. Implications for diagnosis and trauma-informed practices for queer and transgender people are discussed. Additionally, the role of the mental health professional as a social justice advocate is explored, including how social justice frameworks can be incorporated in the counseling environment. © 2023 Springer Publishing Company, LLC and 2012. All rights reserved.
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The objective of this investigation was to compare isokinetic strength, countermovement jump and drop jump variables between high-contributors and low-contributors within NCAA Division I Men’s and Women’s lacrosse athletes. Men’s (N=36) and Women’s (N=30) NCAA Division I lacrosse athletes completed strength testing of the quadriceps and hamstring across three speeds (60°·s−1, 180°·s−1, 300°·s−1), countermovement and drop jumps. To determine the discriminative ability of select lower-limb strength and power characteristics participants were categorized as high-contributors (Males N=18, age=20.3±0.4 yrs, height=183.9±5.5 cm, mass=90.8±5.8 kg; Females N=15, age=20.8±0.8 yrs, height=169.3±6.7 cm, mass=64.1±7.2 kg) or low-contributors (Males N=18, age=19.5±0.2 yrs, height=184.1±5.6 cm; mass=87.9±8.1 kg; Females N=15, age=19.7±0.2 yrs, height=169.8±7.0 cm, mass=62.9±7.7 kg ) based upon the number of games the participants competed in during the regular season. Within the male cohort, moderate significant (p−1 (d=0.69) and peak power in countermovement jump (d=0.68). Within the women’s cohort a large (d=0.87) significant difference (p−1. Hamstring strength and lower-limb power are important strength measures for lacrosse performance and should be prioritized in training prescription for lacrosse athletes.
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Quark interactions with topological gluon configurations can induce local chirality imbalance and parity violation in quantum chromodynamics, which can lead to the chiral magnetic effect (CME)—an electric charge separation along the strong magnetic field in relativistic heavy-ion collisions. The CME-sensitive azimuthal correlator observable (Δγ) is contaminated by background arising, in part, from resonance decays coupled with elliptic anisotropy (v2). We report here differential measurements of the correlator as a function of the pair invariant mass (minv) in 20–50% centrality Au+Au collisions at √sNN=200 GeV by the STAR experiment at the BNL Relativistic Heavy Ion Collider. Strong resonance background contributions to Δγ are observed. At large minv where this background is significantly reduced, the Δγ value is found to be significantly smaller. An event-shape-engineering technique is deployed to determine the v2 background shape as a function of minv. We extract a v2-independent and minv-averaged signal Δγsig=(0.03±0.06±0.08)×10−4, or (2±4±5)% of the inclusive Δγ(minv>0.4 GeV/c2)=(1.58±0.02±0.02)×10−4, within pion pT=0.2–0.8 GeV/c and averaged over pseudorapidity ranges of −1<η<−0.05 and 0.05<η<1. This represents an upper limit of 0.23×10−4, or 15% of the inclusive result, at 95% confidence level for the minv-integrated CME contribution.
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At a time of substantial interest in the Blue Economy, it is surprising that sustainability dilemmas and justice components are not well integrated within its academic discourse or policy arena. Reviewing a number of existing U.S. coastal and marine policies, we identify that justice and equity components are essentially missing and advocate for a comprehensive policy framework for a just and inclusive transition for the Blue Economy. Looking forward, we review and critique the policy proposal of Elizabeth Warren’s Blue New Deal. While the current state of the Blue New Deal remains uncertain, we indicate that such a policy framework would integrate justice, equity and inclusivity as part of operationalising the Blue Economy. Given the proposal for a Blue New Deal is relatively new, we propose a research agenda to explore how comprehensive policy frameworks may seek to place justice and inclusivity at the centre of the Blue Economy.
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We report on the use of label-free, native fluorescence (NFL) spectroscopy and machine learning (ML) algorithms to study the correlation of relative tryptophan levels with prostate cancer aggressiveness. Three extensively studied prostate cancer cell lines were used; PC3, an aggressive, androgen-resistant line, with a high tendency to metastasize in vivo, DU-145, a less aggressive cancer cell line, also androgen-resistant, and LNCaP, an androgen sensitive line, which has a low tendency to metastasize. Using an excitation of 300nm, differences in the NFL spectral profiles from these cell lines were found to correlate with changes in the relative concentrations of tryptophan and reduced nicotinamide adenine dinucleotide (NADH). The use of ML may present a powerful tool for the assessment of the likelihood of a cancer to metastasize. This technique could aid in the decision whether to use highly aggressive adjuvant chemotherapy or radiation therapy after surgical resection of a prostate cancer.
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