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The expansion of states and empires often has important consequences for local populations, including increased violence, greater stress, or dietary modifications resulting in changing health conditions. This paper presents the analysis of 73 skeletons from the Cusco site of Ak’awillay, shedding light on diet, health, and violence in the Middle Horizon. Results indicate that the people of Ak’awillay led a rigorous lifestyle and suffered from more nutritional deficiencies compared to previous populations, possibly pointing to increased maize consumption. However, the low incidence of trauma at Ak’awillay and other Cusco sites suggest that the Wari presence in Cusco was not entrenched in violence.

We extend results first announced by Franz et al., that identified vA 351 = H346 in the Hyades as a multiple star system containing a white dwarf. With Hubble Space Telescope Fine Guidance Sensor fringe tracking and scanning, and more recent speckle observations, all spanning 20.7 years, we establish a parallax, relative orbit, and mass fraction for two components, with a period, and total mass 2.1 . With ground-based radial velocities from the McDonald Observatory Otto Struve 2.1 m Telescope Sandiford Spectrograph, and Center for Astrophysics Digital Speedometers, spanning 37 years, we find that component B consists of BC, two M dwarf stars orbiting with a very short period ( days), having a mass ratio / = 0.95. We confirm that the total mass of the system can only be reconciled with the distance and component photometry by including a fainter, higher-mass component. The quadruple system consists of three M dwarfs (A, B, C) and one white dwarf (D). We determine individual M dwarf masses = 0.53 ± 0.10 , = 0.43 ± 0.04 , and = 0.41 ± 0.04 . The white dwarf mass, 0.54 ± 0.04 , comes from cooling models, an assumed Hyades age of 670 Myr, and consistency with all previous and derived astrometric, photometric, and radial velocity results. Velocities from Hα and He i emission lines confirm the BC period derived from absorption lines, with similar (He i) and higher (Hα) velocity amplitudes. We ascribe the larger Hα amplitude to emission from a region each component shadows from the other, depending on the line of sight.

Black and Latinx communities have faced disproportionate harm from the COVID-19 pandemic. Increasing COVID-19 vaccine acceptance and access has the potential to mitigate mortality and morbidity from COVID-19 for all communities, including those most impacted by the pandemic.To investigate and understand factors associated with facilitating and obstructing COVID-19 vaccine access and acceptance among Black and Latinx communities.This community-partnered qualitative study conducted semistructured, in-depth focus groups with Black and Latinx participants from March 17 to March 29, 2021, using a secure video conferencing platform. Participants were recruited through emails from local community-based organizations, federally qualified health centers, social service agencies, the New Haven, Connecticut, Health Department, and in-person distribution of study information from community health workers. A total of 8 focus groups were conducted, including 4 in Spanish and 4 in English, with 72 participants from a diverse range of community roles, including teachers, custodial service workers, and health care employees, in New Haven, Connecticut. Data were analyzed from March 17 to July 30, 2021.Interviews were audio-recorded, transcribed, translated, and analyzed using an inductive content analysis approach. Themes and subthemes were identified on the acceptability and accessibility of the COVID-19 vaccine among participants who identified as Black and/or Latinx.Among 72 participants, 36 (50%) identified as Black, 28 (39%) as Latinx, and 8 (11%) as Black and Latinx and 56 (78%) identified as women and 16 (22%) identified as men. Participants described 3 major themes that may represent facilitators and barriers to COVID-19 vaccinations: pervasive mistreatment of Black and Latinx communities and associated distrust; informing trust via trusted messengers and messages, choice, social support, and diversity; and addressing structural barriers to vaccination access.The findings of this qualitative study may impact what health care systems, public health officials, policy makers, health care practitioners, and community leaders can do to facilitate equitable uptake of the COVID-19 vaccine. Community-informed insights are imperative to facilitating COVID-19 vaccine access and acceptance among communities hardest hit by the pandemic. Preventing the further widening of inequities and addressing structural barriers to vaccination access are vital to protecting all communities, especially Black and Latinx individuals who have experienced disproportionate death and loss from COVID-19.

The purpose of this multisite, randomized, pretest/posttest quasi-experimental study was to compare student nurse competency, learning retention, and perceived student support after exposure to a deliberate practice debriefing versus standardized debriefing. Fifty undergraduate students participated in the complex response to rescue simulation. The intervention group had significantly higher total mean and three subscale scores on the competency tool than the comparison group, although differences in learning retention and student support were not significant. This study provides preliminary support for the effectiveness of deliberate practice debriefing to enhance students’ mastery of skills and behaviors in complex simulations.

The STAR Collaboration reports measurements of the transverse single-spin asymmetry (TSSA) of inclusive π0 at center-of-mass energies (√s) of 200 GeV and 500 GeV in transversely polarized proton-proton collisions in the pseudo-rapidity region 2.7 to 4.0. The results at the two different energies show a continuous increase of the TSSA with Feynman-x, and, when compared to previous measurements, no dependence on √s from 19.4 GeV to 500 GeV is found. To investigate the underlying physics leading to this large TSSA, different topologies have been studied. π0 with no nearby particles tend to have a higher TSSA than inclusive π0. The TSSA for inclusive electromagnetic jets, sensitive to the Sivers effect in the initial state, is substantially smaller, but shows the same behavior as the inclusive π0 asymmetry as a function of Feynman-x. To investigate final-state effects, the Collins asymmetry of π0 inside electromagnetic jets has been measured. The Collins asymmetry is analyzed for its dependence on the π0 momentum transverse to the jet thrust axis and its dependence on the fraction of jet energy carried by the π0. The asymmetry was found to be small in each case for both center-of-mass energies. All the measurements are compared to QCD-based theoretical calculations for transverse-momentum-dependent parton distribution functions and fragmentation functions. Some discrepancies are found, which indicates new mechanisms might be involved.

The STAR collaboration reports a measurement of the transverse single-spin asymmetries, AN, for neutral pions produced in polarized proton collisions with protons (pp), with aluminum nuclei (pAl) and with gold nuclei (pAu) at a nucleon-nucleon center-of-mass energy of 200 GeV. Neutral pions are observed in the forward direction relative to the transversely polarized proton beam, in the pseudorapidity region 2.7<η<3.8. Results are presented for π0s observed in the STAR forward meson spectrometer electromagnetic calorimeter in narrow Feynman x (xF) and transverse momentum (pT) bins, spanning the range 0.17<xF<0.81 and 1.7<pT<6.0 GeV/c. For fixed xF<0.47, the asymmetries are found to rise with increasing transverse momentum. For larger xF, the asymmetry flattens or falls as pT increases. Parametrizing the ratio r(A)≡AN(pA)/AN(pp)=AP over the kinematic range, the ratio r(A) is found to depend only weakly on A, with ⟨P⟩=−0.027±0.005. No significant difference in P is observed between the low-pT region, pT<2.5 GeV/c, where gluon saturation effects may play a role, and the high-pT region, pT>2.5 GeV/c. It is further observed that the value of AN is significantly larger for events with a large-pT isolated π0 than for events with a nonisolated π0 accompanied by additional jetlike fragments. The nuclear dependence r(A) is similar for isolated and nonisolated π0 events.

Body and canine size dimorphism in fossils inform sociobehavioral hypotheses on human evolution and have been of interest since Darwin’s famous reflections on the subject. Here, we assemble a large dataset of fossil canines of the human clade, including all available Ardipithecus ramidus fossils recovered from the Middle Awash and Gona research areas in Ethiopia, and systematically examine canine dimorphism through evolutionary time. In particular, we apply a Bayesian probabilistic method that reduces bias when estimating weak and moderate levels of dimorphism. Our results show that Ar. ramidus canine dimorphism was significantly weaker than in the bonobo, the least dimorphic and behaviorally least aggressive among extant great apes. Average male-to-female size ratios of the canine in Ar. ramidus are estimated as 1.06 and 1.13 in the upper and lower canines, respectively, within modern human population ranges of variation. The slightly greater magnitude of canine size dimorphism in the lower than in the upper canines of Ar. ramidus appears to be shared with early Australopithecus, suggesting that male canine reduction was initially more advanced in the behaviorally important upper canine. The available fossil evidence suggests a drastic size reduction of the male canine prior to Ar. ramidus and the earliest known members of the human clade, with little change in canine dimorphism levels thereafter. This evolutionary pattern indicates a profound behavioral shift associated with comparatively weak levels of male aggression early in human evolution, a pattern that was subsequently shared by Australopithecus and Homo. © 2021 National Academy of Sciences. All rights reserved.

The present study objectives were to examine the performance of the new M-CHAT-R algorithm to the original M-CHAT algorithm. The main purpose was to examine if the algorithmic changes increase identification of children later diagnosed with ASD, and to examine if there is a trade-off when changing algorithms. We included 54,463 screened cases from the Norwegian Mother and Child Cohort Study. Children were screened using the 23 items of the M-CHAT at 18 months. Further, the performance of the M-CHAT-R algorithm was compared to the M-CHAT algorithm on the 23-items. In total, 337 individuals were later diagnosed with ASD. Using M-CHAT-R algorithm decreased the number of correctly identified ASD children by 12 compared to M-CHAT, with no children with ASD screening negative on the M-CHAT criteria subsequently screening positive utilizing the M-CHAT-R algorithm. A nonparametric McNemar's test determined a statistically significant difference in identifying ASD utilizing the M-CHAT-R algorithm. The present study examined the application of 20-item MCHAT-R scoring criterion to the 23-item MCHAT. We found that this resulted in decreased sensitivity and increased specificity for identifying children with ASD, which is a trade-off that needs further investigation in terms of cost-effectiveness. However, further research is needed to optimize screening for ASD in the early developmental period to increase identification of false negatives. © 2021 The Authors. Autism Research published by International Society for Autism Research and Wiley Periodicals LLC.

Across the planet, winter de-icing practices have caused secondary salinization of freshwater habitats. Many amphibians are vulnerable because of permeable skin and reliance on small ponds, where salinity can be high. Early developmental stages of amphibians are especially sensitive to salt, and larvae developing in salt-polluted environments must osmoregulate through ion exchange in gills. Though ionoregulation in amphibian gills is generally understood, the role of gill morphology remains poorly described. Yet gill structure should affect ionoregulatory capacity, for instance in terms of available surface area. As larval amphibian gills also play critical roles in gas exchange and foraging, changes in gill morphology from salt pollution potentially affect not only osmoregulation, but also respiration and feeding. Here, we used an exposure experiment to quantify salinity effects on larval gill morphology in wood frogs (Rana sylvatica). We measured a suite of morphological traits on gill tufts—where ionoregulation and gas exchange occur—and on gill filters used in feeding. Larvae raised in elevated salinity developed larger gill tufts but with lower surface area to volume ratio. Epithelial cells on these tufts were less circular but occurred at higher densities. Gill filters showed increased spacing, likely reducing feeding efficiency. Many morphological gill traits responded quadratically, suggesting that salinity might induce plasticity in gills at intermediate concentrations until energetic demands exceed plasticity. Together, these changes likely diminish ionoregulatory and respiratory functionality of gill tufts, and compromise feeding functionality of gill filters. Thus, a singular change in aquatic environment from a widespread pollutant appears to generate a suite of consequences via changes in gill morphology. Critically, these changes in traits likely compound the severity of fitness impacts in populations dwelling in salinized environments, whereby ionoregulatory energetic demands should increase respiratory and foraging demands, but in individuals who possess structures poorly adapted for these functions. © 2021 Elsevier Ltd

Accurate characterization of sexual dimorphism is crucial in evolutionary biology because of its significance in understanding present and past adaptations involving reproductive and resource use strategies of species. However, inferring dimorphism in fossil assemblages is difficult, particularly with relatively low dimorphism. Commonly used methods of estimating dimorphism levels in fossils include the mean method, the binomial dimorphism index, and the coefficient of variation method. These methods have been reported to overestimate low levels of dimorphism, which is problematic when investigating issues such as canine size dimorphism in primates and its relation to reproductive strategies. Here, we introduce the posterior density peak (pdPeak) method that utilizes the Bayesian inference to provide posterior probability densities of dimorphism levels and within-sex variance. The highest posterior density point is termed the pdPeak. We investigated performance of the pdPeak method and made comparisons with the above-mentioned conventional methods via 1) computergenerated samples simulating a range of conditions and 2) application to canine crown-diameter datasets of extant known-sex anthropoids. Results showed that the pdPeak method is capable of unbiased estimates in a broader range of dimorphism levels than the other methods and uniquely provides reliable interval estimates. Although attention is required to its underestimation tendency when some of the distributional assumptions are violated, we demonstrate that the pdPeak method enables a more accurate dimorphism estimate at lower dimorphism levels than previously possible, which is important to illuminating human evolution. © 2021 National Academy of Sciences. All rights reserved.

The operation and planning of distribution grids require the joint processing of measurements from different grid locations. Since measurement devices in low-and medium-voltage grids lack precise clock synchronization, it is important for data management platforms of distribution system operators to be able to account for the impact of nonideal clocks on measurement data. This paper formally introduces a metric termed Additive Alignment Error to capture the impact of misaligned averaging intervals of electrical measurements. A trace-driven approach for retrieval of this metric would be computationally costly for measurement devices, and therefore, it requires an online estimation procedure in the data collection platform. To overcome the need of transmission of high-resolution measurement data, this paper proposes and assesses an extension of a Markov-modulated process to model electrical traces, from which a closed-form matrix analytic formula for the Additive Alignment Error is derived. A trace-driven assessment confirms the accuracy of the model-based approach. In addition, the paper describes practical settings where the model can be utilized in data management platforms with significant reductions in computational demands on measurement devices. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Effective family planning methods are shown to save lives, contribute to gender equality, and boost economic development. Mass media communication campaigns in low- and middle-income countries have been effective in increasing contraceptive use, although the strategies that increase the likelihood of success are unclear. The present study uses meta-analyses to uncover the average effect of media campaigns on family planning behaviors in low- and middle-income countries and to examine the effectiveness of two communication strategies: entertainment-education and advertising/public service announcements. Results indicated that mass media-delivered family planning campaigns have a positive impact on family planning behaviors: d = 0.19, 95% CI [0.15, 0.24] for women (k = 64), d = 0.16, 95% CI [0.11, 0.21] for men (k = 27), and d = 0.20, 95% CI [0.17, 0.23] for an undifferentiated target group of men and women (k = 37). The use of an entertainment-education format, often in addition to campaign advertising messages, was associated with greater campaign success rates for women. Men, however, responded negatively to education-entertainment and positively to campaigns using only advertising and public service announcement formats. Recommendations for future family planning mass media campaigns and academic research opportunities are discussed. © 2021 The Population Council, Inc.

Background: It is crucial to support students in better understanding water and sustainability issues because water plays a vital role in maintaining global ecosystems, including human life. A wide range of curricular and instructional supports like those embodied in model-based learning (MBL) are necessary for teachers to engage students in the core epistemic commitments of the Next-Generation Science Standards (NGSS). Purpose: The main purpose of this study is to inform theory about students’ early attempts to engage in the complex kinds of sensemaking experiences inherent in the Framework for K-12 Science Education and the NGSS. Sample: Data for this study was collected from 74 10th grade students in a high school in the Northwest region of the New England state. Design and Methods: An explanatory sequential mixed-method research design was used to examine students’ learning outcomes, and to better understand these outcomes in connection to their experiences engaging in modeling in the MBL curriculum unit. Results: The results indicated that students’ model scores, the number of concepts in models, and the coherence and sophistication of models improved between their initial and final models. Additionally, the following patterns emerged related to ways in which students engaged in the practice of modeling: (1) students attempted to directly represent what they observed, (2) they struggled to pictorially express complex patterns or mechanisms, and (3) students experienced difficulties representing models from a diverse range of perspectives. Conclusion: The patterns identified across student models, as well as their reports of experiences related to the MBL unit implementation, provided insight into student experiences with models, while also providing meaningful implications for the refinement of the MBL curriculum unit investigated in this research specifically, while informing approaches MBL curricular units aimed at supporting NGSS implementation efforts more generally. © 2021 Informa UK Limited, trading as Taylor & Francis Group.

The COVID-19 pandemic has disproportionately affected racial and ethnic minority groups in the United States. Although a promising solution of the COVID-19 vaccination offers hope, disparities in access again threaten the health of these communities. Various explanations have arisen for the cause of disparate vaccination rates among racial and ethnic minorities, including discussion of vaccine hesitancy. Conversely, the role of vaccine accessibility rooted in structural racism as a driver in these disparities should be further explored. This paper discusses the impact of structural barriers on racial and ethnic disparities in COVID-19 vaccine uptake. We also recommend public health, health system, and community-engaged approaches to reduce racial disparities in COVID-19 disease and mortality. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

A team of systematic reviewers successfully completed a government-commissioned review of ‘what works to improve post-school outcomes for youth with disabilities’ in 2012. Despite its success, interviews with 10 review team members revealed dissatisfaction with the process and indifference to its outcomes. The purpose of our analysis was to examine how the systematic review process itself led to review team members’ feelings of indifference, resignation, and pessimism. Drawing on the writings of Henry Giroux, Gert Biesta, and Hanna Arendt that warn of the death of democracy and the rise of totalitarianism, we explored how the systematic review certification process, examinations, rules, and structures deadened democratic deliberation and critique necessary, we argue, to conducting good educational science. We end with a call for systematic reviews in education whose researchers, products, and processes remain ethically oriented to keeping democracy alive. © 2021 Informa UK Limited, trading as Taylor & Francis Group.