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Abelisauridae were medium to large-bodied carnivorous dinosaurs with short, ornamented skulls, poorly recurved ziphodont teeth, and reduced forelimbs. They were the dominant terrestrial carnivores in many Gondwanan ecosystems during the Cretaceous. Their Jurassic origin, primarily based on the putative abelisaurid Eoabelisaurus from the Early Jurassic of Patagonia, remains debated, with many authors considering Abelisauridae as a strictly Cretaceous theropod radiation. Here, we describe several historically and stratigraphically important isolated theropod teeth from Gondwana, identified as belonging to abelisaurids using new cladistic and machine learning methods. Dental evolution in Abelisauridae was additionally explored using an updated version of a dentition-based data matrix focused on ceratosaurs. Results of this study show that the evolution of the dentition in abelisaurids was marked by a decrease in size of the mesialmost dentary teeth and the displacement of the tallest crowns towards the middle part of the maxilla. Two isolated abelisaurid teeth from the Late Cretaceous of India and Patagonia were also identified as the earliest published record of a non-avian theropod in Asia and an abelisaurid in Argentina, respectively. More importantly, isolated theropod teeth confidently referred to Abelisauridae from the Middle Jurassic of Madagascar provide additional support for the emergence of this clade in Gondwana before the Late Jurassic and reveal that the acquisition of abelisaurid dental traits occurred early in the evolutionary history of one of the most successful radiations of non-avian theropods from Europe and the Southern Hemisphere. © 2025 Asociación Paleontológica Argentina (APA)
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High-energy, heavy-ion collisions can create local domains of chirality-imbalanced quarks, reflecting the topological features of quantum chromodynamics. The chiral magnetic effect (CME) predicts an electric charge separation of quarks in such topological domains along the magnetic field (B) generated by the passing of two high-Z nuclei. We use a correlation observable Δγ112 between charged meson pairs to detect the CME-induced charge separation and a novel event shape selection (ESS) method to mitigate the background effects related to elliptic flow (v2). The ESS method classifies events based on the emission pattern of final-state particles and determines Δγ(Formula presented) from the zero-flow limit. We reconstruct the B field direction from the spectator nucleons, which minimizes backgrounds unrelated to the collective motion of the system. In this work, we report the measurements of Δγ112 and a background indicator Δγ132 in Au + Au collisions from the Brookhaven National Laboratory Relativistic Heavy Ion Collider (RHIC) Beam Energy Scan phase II and at the top RHIC energy. After background suppression, Δγ(Formula presented) aligns with zero, and Δγ(Formula presented) is reduced to no more than 20% of Δγ112. We observe a finite residual charge separation with 2.5σ, 3σ, and 3.2σ significance in the 20-50% centrality range of Au + Au collisions at 11.5, 14.6, and 19.6 GeV. The results at 17.3 and 27 GeV also show positive values but with a lower significance of 1.3σ and 1.1σ, respectively. The corresponding ΔγΈ5ΕΕ values at 7.7, 9.2, and 200 GeV are consistent with zero within uncertainties. © (2026), (American Physical Society). All right reserved.
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Rapidity-odd directed flow v 1 measurements are presented for K ± and KS0 in Au + Au collisions for sNN from 3.0 to 3.9 GeV with the STAR experiment. For comparison, v 1 of π ± , protons, and Λ from the same collisions are also discussed. The mid-rapidity v 1 slope dv1/dy|y=0 for protons and Λ is positive in these collisions. On the other hand, v 1 slope of kaons exhibits a strong pT dependence: negative at pT< 0.6 GeV/ c and positive at higher pT. A similar pT dependence is also evident for the v 1 slope of charged pions. Compared to the spectator-removed calculations in Au+Au collisions at sNN= 3.0–3.9 GeV, the JAM model demonstrates a pronounced shift of the v 1 slopes of mesons towards the negative direction. It suggests that the shadowing effect of the spectators plays an important role in the observed kaon anti-flow at low pT in the high baryon density region of non-central collisions. © 2026 The Authors.
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BACKGROUND: Following greater than or equal to 48-h intubation, one-third of acute respiratory failure (ARF) patients aspirate. Laryngeal edema has been identified as a potentially modifiable risk factor of post-extubation aspiration. The aim of this case-control study was to characterize the anatomical distribution of post-extubation laryngeal edema and to correlate anatomical laryngeal edema severity with aspiration risk in ARF survivors. The study also assessed whether patient weakness influenced the relationship between laryngeal edema and aspiration risk. METHODS: Flexible endoscopic evaluation of swallowing (FEES) videos from 120 patients (60 aspirators, 60 non-aspirators) were obtained from a previous multicenter observational study. Laryngeal edema was rated in eight locations using the Revised Patterson Edema Scale (RPES). Aspiration status was determined by a clinical rater core, and patient weakness was assessed using peak cough flow and pharyngeal medialization outcomes. Bivariate associations with aspiration were tested using Fisher's exact tests. Logistic regression models were used to test for associations between anatomical laryngeal edema severity and risk of aspiration. Logistic regression models were fit to explore whether weakness modified the relationship between edema and aspiration risk. RESULTS: The strongest anatomic predictor of post-extubation aspiration was the presence of aryepiglottic fold edema (adjusted odds ratio, aOR = 5.74, p = 0.009, FDR-adjusted p = 0.073). Weakness independently increased aspiration risk [aOR = 3.93 (95%CI = 1.42, 11.9), p = 0.011], but without evidence of an interaction effect with edema (p = 0.15). CONCLUSION: These findings can inform future research studying the influence of laryngeal edema on aspiration risk, as well as interventional studies aimed at reducing adverse outcomes associated with laryngeal edema. © 2026. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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NASA’s TESS mission has unveiled a plethora of eclipsing binaries (EBs), among them hundreds of triples and higher-order, hierarchical systems. These complex targets require follow-up observations to enable full characterization of system architectures and identify the most compact multiples expected to undergo the most dramatic dynamical evolution. We report first results from a long-term effort to perform such follow-up, focusing here on multiband speckle imaging of a majority (57) of the sample of 97 quadruple- and higher-order eclipsing binaries (Q+EBs) identified via TESS light curves by V. B. Kostov et al. Diffraction-limited imaging with the Differential Speckle Survey Instrument on the Astrophysical Research Consortium 3.5 m telescope and HRCam on the Southern Astrophysical Research 4.1 m telescope reveals nearly 60% of the 57 to resolve into two sources separated by ≥0. ″03. For these partly resolved systems, we report derived characteristics (e.g., relative position angle, angular separation, and magnitude differences in multiple passbands) from the speckle imaging. We find those Q+EBs partly resolved with 4 m class telescopes to have significantly inflated Gaia parallax errors and large Gaia renormalized unit weight errors, particularly for systems with separations comparable to Gaia’s resolution limit (∼0. ″6). For unresolved systems we report upper limits on angular and linear projected separations. We find two partly resolved Q+EBs with wide linear separations having eclipse timing variations that are therefore candidates of higher-than-quadruple multiplicity. Finally, we demonstrate how speckle imaging of resolved Q+EBs during an eclipse can clarify which speckle-resolved Q+EB subsystem is associated with a particular set of TESS eclipses. © 2025. The Author(s). Published by the American Astronomical Society.
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Background: The experiences of patients with COVID-19 and their families manifested the most devastating effects of family separation since the 1918 Spanish influenza pandemic and, with it, a call for solutions to patient isolation and its effect on family mental health. Objective: This study examined the recent experiences of families of critical care (intensive care unit; ICU) patients related to anxiety and depression (AD), satisfaction with clinician-family communication, and counseling from mental health and social services. This study explored correlations between these factors and family interest in mobile health (mHealth) designed to improve information flow and communication from patient bedside to remote families. Methods: Using a 36-question quantitative survey, we collected 97 responses over 6 months. We selected participants by using a convenience sampling strategy. To analyze data, we applied descriptive and inferential statistics. Participants represented a spectrum of ages, relationships to patients, and races (n=78, 80% White; n=17, 18% Black; n=2, 2% other races). Approximately 17% (n=16) of the patients were admitted for cancer, 13% (n=13) were admitted for COVID-19, and 21% (n=20) were admitted for other conditions. Results: The mean score for remote families’ satisfaction with patient health updates from the bedside and mental health services was 2.94 (SD 1.31), whereas that for phone communication was lower on average. The mean scores of family AD levels were elevated, and levels were higher among family members during the ICU stay than after discharge. These findings confirmed evidence of a negative correlation between transportation difficulties and satisfaction with the frequency of information provided (r=−0.284; P=.005), suggesting that, with the increase in transportation challenges, families become less satisfied with the frequency of patient health information. Family members expressed strong interest in using mHealth information and communication services (mean 8.34, SD 1.98) and having easy access to social workers to manage AD (mean 8.29, SD 2.03). Families experiencing higher levels of anxiety during patients’ ICU stays had significantly greater interest in the use of an mHealth app that would provide direct access to social workers (r=0.326; P<.001), in using an mHealth videoconferencing app (r=0.319; P=.002), and in overall mHealth app use (r=0.322; P<.001). Conclusions: Family members experienced high levels of AD during patient ICU admission, as well as after discharge even though their mental health challenges were reduced. Families were highly dissatisfied with the frequency of health updates, with lower satisfaction reported among those who faced difficulties arranging transportation or lived further from the hospital. Modest but statistically significant correlations were observed between family members’ reported mental health status during ICU stays and an interest in an mHealth app that could provide access to real-time bedside information, facilitate communication with bedside nurses, and support connections with social workers. ©Anthony Faiola, Saira Soroya, Zhonglin Hao, Reinhold Munker.
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This paper examines a small group of sixteenth-century manuscript maps made in Normandy to argue that the placement and properties of the female figures positioned on them were deliberate and strategic. It inventories the locations where female figures can be found on the maps and concludes that the women served as elements not only of design and decoration but also of desire, intended to attract the interest and enhance the appeal of the distant sites where French navigators hoped to establish trade and settlement. The female figures, often nude and prominently placed, communicated the beauty and fertility of the potential colonies, and their passivity and tractable character. The women on the maps were both bait and reward to the powerful male viewers to whom the maps were addressed. © 2026 British Cartographic Society.
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When most people think of the use of animals in traditional systems of medicine, what springs to mind is one kind or another of megafauna such as rhinoceros, bears, sharks, and others. Sometimes more mundane creatures such as pangolins are included. However, invertebrates and substances produced by them have been used in Asian systems of medicine since the earliest records of materia medica from the region were created. Animals used range from shellfish and crustaceans to various insects and insect products such as cocoons, honey, and beeswax. In terms of their role in the food chain, and as pollinators, invertebrates are as crucial to the health, indeed the survival, of ecosystems in Asia and elsewhere as are megafauna. Loss and degradation of habitat is probably affecting more invertebrates than medicalization. Still, the expansion of medicalization in Asia and beyond is contributing to the danger many populations of invertebrates currently face. This article gives an overview of the place of invertebrates in Vietnamese traditional medicine and then presents a case study of two varieties of honey- and beeswax-producing bees found in northern mainland Southeast Asia and southern China: Apis dorsata F. and Apis cerana. © C. Michele Thompson, 2026. Published with license by Koninklijke Brill BV
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We report measurements of charmonium sequential suppression in Ru+Ru and Zr+Zr collisions at sNN=200 GeV with the STAR experiment at the Relativistic Heavy Ion Collider (RHIC). The inclusive yield ratio of ψ(2S) to J/ψ as a function of transverse momentum is reported, along with the centrality dependence of the double ratio, defined as the ψ(2S) to J/ψ ratio in heavy-ion collisions relative to that in p+p collisions. In the 0-80% centrality class, the double ratio is found to be 0.41±0.10 (stat)±0.03 (syst)±0.02 (ref), lower than unity with a significance of 5.6 standard deviations. This provides experimental evidence that ψ(2S) is significantly more suppressed than J/ψ in heavy-ion collisions at RHIC. This sequential suppression pattern seems to increase from peripheral to central collisions, but with no significant dependence on the transverse momentum. © 2026 American Physical Society.
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The same dataset can be analysed in different justifiable ways to answer the same research question, potentially challenging the robustness of empirical science1-3. In this crowd initiative, we investigated the degree to which research findings in the social and behavioural sciences are contingent on analysts' choices. We examined a stratified random sample of 100 studies published between 2009 and 2018, in which, for one claim per study, at least five reanalysts independently reanalysed the original data. The statistical appropriateness of the reanalyses was assessed in peer evaluations, and the robustness indicators were inspected along a range of research characteristics and study designs. We found that 34% of the independent reanalyses yielded the same result (within a tolerance region of ±0.05 Cohen's d) as the original report; with a four times broader tolerance region, this indicator increased to 57%. Of the reanalyses conducted, 74% reached the same conclusion as the original investigation, 24% yielded no effects or inconclusive results and 2% reported the opposite effect. This exploratory study indicates that the common single-path analyses in social and behavioural research should not be simply assumed to be robust to alternative analyses4. Therefore, we recommend the development and use of practices to explore and communicate this neglected source of uncertainty. © 2026. The Author(s), under exclusive licence to Springer Nature Limited.
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The Solenoidal Tracker at RHIC (STAR) experiment at the Relativistic Heavy Ion Collider reports new measurements of jet quenching based on the semi-inclusive distribution of charged-particle jets recoiling from direct photon (γdir) and neutral pion (π0) triggers in pp and central Au + Au collisions at √sNN = 200 GeV for triggers in the range 9 < ET trig < 20 GeV. The datasets have integrated luminosities of 3.9 nb−1 for Au + Au and 23 pb−1 for pp collisions. Jets are reconstructed using the anti-kT algorithm with resolution parameters R = 0.2 and 0.5. The large uncorrelated jet background in central Au + Au collisions is corrected using a mixed-event approach, which enables precise charged-particle jet measurements at low transverse momentum pch T,jet and large R. Recoil-jet distributions are reported in the range pch T,jet < 25 GeV/c. Comparison of the distributions measured in pp and Au + Au collisions reveals strong medium-induced jet yield suppression for R = 0.2 with markedly less suppression for R = 0.5. Comparison is also made to theoretical models incorporating jet quenching. These data provide new insight into the mechanisms underlying jet quenching and the angular dependence of medium-induced jet-energy transport and provide new constraints on modeling such effects. © 2025 American Physical Society
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Background: Following greater than or equal to 48-h intubation, one-third of acute respiratory failure (ARF) patients aspirate. Laryngeal edema has been identified as a potentially modifiable risk factor of post-extubation aspiration. The aim of this case–control study was to characterize the anatomical distribution of post-extubation laryngeal edema and to correlate anatomical laryngeal edema severity with aspiration risk in ARF survivors. The study also assessed whether patient weakness influenced the relationship between laryngeal edema and aspiration risk. Methods: Flexible endoscopic evaluation of swallowing (FEES) videos from 120 patients (60 aspirators, 60 non-aspirators) were obtained from a previous multicenter observational study. Laryngeal edema was rated in eight locations using the Revised Patterson Edema Scale (RPES). Aspiration status was determined by a clinical rater core, and patient weakness was assessed using peak cough flow and pharyngeal medialization outcomes. Bivariate associations with aspiration were tested using Fisher’s exact tests. Logistic regression models were used to test for associations between anatomical laryngeal edema severity and risk of aspiration. Logistic regression models were fit to explore whether weakness modified the relationship between edema and aspiration risk. Results: The strongest anatomic predictor of post-extubation aspiration was the presence of aryepiglottic fold edema (adjusted odds ratio, aOR = 5.74, p = 0.009, FDR-adjusted p = 0.073). Weakness independently increased aspiration risk [aOR = 3.93 (95%CI = 1.42, 11.9), p = 0.011], but without evidence of an interaction effect with edema (p = 0.15). Conclusion: These findings can inform future research studying the influence of laryngeal edema on aspiration risk, as well as interventional studies aimed at reducing adverse outcomes associated with laryngeal edema. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2026.
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Glioma is the most common brain neoplasm that features aggressive behavior with a dismal prognosis. Isocitrate dehydrogenase (IDH) gene mutation in glioma is an early genetic event in gliomagenesis that occurs in virtually every tumor cell and can cause profound metabolic changes. In this manuscript, we report for the first time the analysis of Raman optical signatures of IDH genotypes for human glioma using visible resonance Raman (VRR) spectroscopy. We demonstrated that VRR is a rapid, label-free, and objective method as an alternative to the existing methods for the rapid intraoperative determination of IDH mutation status with high accuracy. This study shows AI-assisted VRR has the potential to provide a new optical molecular biomarker and perform early diagnosis of glioma, which is of great importance for current guiding surgical strategies and even for targeting in situ therapies in the future. © 2026 Wiley-VCH GmbH.
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Inhibitory Smads (I-Smads) regulate TGF-β/BMP signaling through multiple distinct mechanisms, but whether different tissues preferentially employ specific mechanisms remains unknown. To address this question, we performed structure–function analyses of the Drosophila I-Smad, Dad, and its vertebrate orthologs Smad6 and Smad7 in neural and wing tissues, measuring outputs of BMP signaling in vivo. We identified a 24–amino acid putative DNA-binding domain within the MH1 domain of Dad that is essential for inhibitory function in wing tissue but unessential in neural tissue. Structural analyses revealed that ΔDNA-binding domain disrupts a β-hairpin structure homologous to R-Smad DNA-binding regions. We also found that Dad requires an intact MH1 domain to disrupt wing development, whereas either MH1 or MH2 can independently disrupt BMP signaling in motor neurons. These findings support a model where Dad functions through MH1-mediated transcriptional regulation in wing primordium, but through multiple mechanisms in neurons. Comparative analysis revealed that vertebrate I-Smad orthologs also show tissue-specific activity patterns, with structural predictions suggesting that Smad6 retains ancestral DNA-binding capacity, whereas Smad7 has evolved enhanced MH2-mediated functions. These results reveal context-dependent mechanisms of I-Smads that further the understanding of TGF-β/BMP pathway regulation. © 2026, Life Science Alliance, LLC. All rights reserved.
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The fear of missing out (FoMO)—the apprehension that others are having rewarding experiences in one's absence—has been linked to diminished well-being and maladaptive behaviors. While research has primarily focused on neurotypical populations, little is known about how FoMO associates with and manifests in neurodiverse cognitive profiles. The present study examined associations between general and workplace FoMO and individual differences in ADHD symptoms, autistic traits, and internal cognitive representation styles (visual imagery, internal verbalization, representational manipulation) in a U.S. sample of full-time employees ( N = 302). Across both regression and machine learning analyses, ADHD symptoms emerged as the most robust and consistent predictor of FoMO in both domains. Visual imagery significantly predicted general FoMO, whereas internal verbalization and representational manipulation showed stronger associations with workplace FoMO. Autistic traits, as measured by the AQ-10, were not significantly related to FoMO. Classification models (e.g., logistic regression, SVM) distinguished high versus low FoMO participants with moderate-to-high accuracy, with ADHD symptoms consistently ranked as the most influential feature. These findings extend the literature by highlighting domain-specific predictors of FoMO and the potential of neurodiversity-informed approaches for understanding and addressing FoMO in both social and occupational settings. © 2026 Elsevier Ltd.
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