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BACKGROUND: The experiences of patients with COVID-19 and their families manifested the most devastating effects of family separation since the 1918 Spanish influenza pandemic and, with it, a call for solutions to patient isolation and its effect on family mental health. OBJECTIVE: This study examined the recent experiences of families of critical care (intensive care unit; ICU) patients related to anxiety and depression (AD), satisfaction with clinician-family communication, and counseling from mental health and social services. This study explored correlations between these factors and family interest in mobile health (mHealth) designed to improve information flow and communication from patient bedside to remote families. METHODS: Using a 36-question quantitative survey, we collected 97 responses over 6 months. We selected participants by using a convenience sampling strategy. To analyze data, we applied descriptive and inferential statistics. Participants represented a spectrum of ages, relationships to patients, and races (n=78, 80% White; n=17, 18% Black; n=2, 2% other races). Approximately 17% (n=16) of the patients were admitted for cancer, 13% (n=13) were admitted for COVID-19, and 21% (n=20) were admitted for other conditions. RESULTS: The mean score for remote families' satisfaction with patient health updates from the bedside and mental health services was 2.94 (SD 1.31), whereas that for phone communication was lower on average. The mean scores of family AD levels were elevated, and levels were higher among family members during the ICU stay than after discharge. These findings confirmed evidence of a negative correlation between transportation difficulties and satisfaction with the frequency of information provided (r=-0.284; P=.005), suggesting that, with the increase in transportation challenges, families become less satisfied with the frequency of patient health information. Family members expressed strong interest in using mHealth information and communication services (mean 8.34, SD 1.98) and having easy access to social workers to manage AD (mean 8.29, SD 2.03). Families experiencing higher levels of anxiety during patients' ICU stays had significantly greater interest in the use of an mHealth app that would provide direct access to social workers (r=0.326; P<.001), in using an mHealth videoconferencing app (r=0.319; P=.002), and in overall mHealth app use (r=0.322; P<.001). CONCLUSIONS: Family members experienced high levels of AD during patient ICU admission, as well as after discharge even though their mental health challenges were reduced. Families were highly dissatisfied with the frequency of health updates, with lower satisfaction reported among those who faced difficulties arranging transportation or lived further from the hospital. Modest but statistically significant correlations were observed between family members' reported mental health status during ICU stays and an interest in an mHealth app that could provide access to real-time bedside information, facilitate communication with bedside nurses, and support connections with social workers.

When most people think of the use of animals in traditional systems of medicine, what springs to mind is one kind or another of megafauna such as rhinoceros, bears, sharks, and others. Sometimes more mundane creatures such as pangolins are included. However, invertebrates and substances produced by them have been used in Asian systems of medicine since the earliest records of materia medica from the region were created. Animals used range from shellfish and crustaceans to various insects and insect products such as cocoons, honey, and beeswax. In terms of their role in the food chain, and as pollinators, invertebrates are as crucial to the health, indeed the survival, of ecosystems in Asia and elsewhere as are megafauna. Loss and degradation of habitat is probably affecting more invertebrates than medicalization. Still, the expansion of medicalization in Asia and beyond is contributing to the danger many populations of invertebrates currently face. This article gives an overview of the place of invertebrates in Vietnamese traditional medicine and then presents a case study of two varieties of honey- and beeswax-producing bees found in northern mainland Southeast Asia and southern China: Apis dorsata F. and Apis cerana. © C. Michele Thompson, 2026. Published with license by Koninklijke Brill BV

We report measurements of charmonium sequential suppression in Ru+Ru and Zr+Zr collisions at sNN=200 GeV with the STAR experiment at the Relativistic Heavy Ion Collider (RHIC). The inclusive yield ratio of ψ(2S) to J/ψ as a function of transverse momentum is reported, along with the centrality dependence of the double ratio, defined as the ψ(2S) to J/ψ ratio in heavy-ion collisions relative to that in p+p collisions. In the 0-80% centrality class, the double ratio is found to be 0.41±0.10 (stat)±0.03 (syst)±0.02 (ref), lower than unity with a significance of 5.6 standard deviations. This provides experimental evidence that ψ(2S) is significantly more suppressed than J/ψ in heavy-ion collisions at RHIC. This sequential suppression pattern seems to increase from peripheral to central collisions, but with no significant dependence on the transverse momentum. © 2026 American Physical Society.

The same dataset can be analysed in different justifiable ways to answer the same research question, potentially challenging the robustness of empirical science1-3. In this crowd initiative, we investigated the degree to which research findings in the social and behavioural sciences are contingent on analysts' choices. We examined a stratified random sample of 100 studies published between 2009 and 2018, in which, for one claim per study, at least five reanalysts independently reanalysed the original data. The statistical appropriateness of the reanalyses was assessed in peer evaluations, and the robustness indicators were inspected along a range of research characteristics and study designs. We found that 34% of the independent reanalyses yielded the same result (within a tolerance region of ±0.05 Cohen's d) as the original report; with a four times broader tolerance region, this indicator increased to 57%. Of the reanalyses conducted, 74% reached the same conclusion as the original investigation, 24% yielded no effects or inconclusive results and 2% reported the opposite effect. This exploratory study indicates that the common single-path analyses in social and behavioural research should not be simply assumed to be robust to alternative analyses4. Therefore, we recommend the development and use of practices to explore and communicate this neglected source of uncertainty. © 2026. The Author(s), under exclusive licence to Springer Nature Limited.

The Solenoidal Tracker at RHIC (STAR) experiment at the Relativistic Heavy Ion Collider reports new measurements of jet quenching based on the semi-inclusive distribution of charged-particle jets recoiling from direct photon (γdir) and neutral pion (π0) triggers in pp and central Au + Au collisions at √sNN = 200 GeV for triggers in the range 9 < ET trig < 20 GeV. The datasets have integrated luminosities of 3.9 nb−1 for Au + Au and 23 pb−1 for pp collisions. Jets are reconstructed using the anti-kT algorithm with resolution parameters R = 0.2 and 0.5. The large uncorrelated jet background in central Au + Au collisions is corrected using a mixed-event approach, which enables precise charged-particle jet measurements at low transverse momentum pch T,jet and large R. Recoil-jet distributions are reported in the range pch T,jet < 25 GeV/c. Comparison of the distributions measured in pp and Au + Au collisions reveals strong medium-induced jet yield suppression for R = 0.2 with markedly less suppression for R = 0.5. Comparison is also made to theoretical models incorporating jet quenching. These data provide new insight into the mechanisms underlying jet quenching and the angular dependence of medium-induced jet-energy transport and provide new constraints on modeling such effects. © 2025 American Physical Society

This timely compendium provides state-of-the-art articles covering research areas in Nanoelectronics, Nanophotonics and Quantum Technologies.Composed of contributions by renowned researchers from both the academia and industry, this useful reference text broadly illustrates relevant aspects of high-performance materials and emerging quantum and nanoscale devices for implementing high-speed electronic systems.

Inhibitory Smads (I-Smads) regulate TGF-β/BMP signaling through multiple distinct mechanisms, but whether different tissues preferentially employ specific mechanisms remains unknown. To address this question, we performed structure–function analyses of the Drosophila I-Smad, Dad, and its vertebrate orthologs Smad6 and Smad7 in neural and wing tissues, measuring outputs of BMP signaling in vivo. We identified a 24–amino acid putative DNA-binding domain within the MH1 domain of Dad that is essential for inhibitory function in wing tissue but unessential in neural tissue. Structural analyses revealed that ΔDNA-binding domain disrupts a β-hairpin structure homologous to R-Smad DNA-binding regions. We also found that Dad requires an intact MH1 domain to disrupt wing development, whereas either MH1 or MH2 can independently disrupt BMP signaling in motor neurons. These findings support a model where Dad functions through MH1-mediated transcriptional regulation in wing primordium, but through multiple mechanisms in neurons. Comparative analysis revealed that vertebrate I-Smad orthologs also show tissue-specific activity patterns, with structural predictions suggesting that Smad6 retains ancestral DNA-binding capacity, whereas Smad7 has evolved enhanced MH2-mediated functions. These results reveal context-dependent mechanisms of I-Smads that further the understanding of TGF-β/BMP pathway regulation.

Let A be a Noetherian local ring with canonical module KA. We characterize A when KA is a torsionless, reflexive, or q-torsionfree module for an integer q ≥ 3. If A is a Cohen–Macaulay ring, H.-B. Foxby proved in 1974 that the A-module KA is q-torsionfree if and only if the ring A is q-Gorenstein. With mild assumptions, we provide a generalization of Foxby’s result to arbitrary Noetherian local rings admitting the canonical module. In particular, since the reflexivity of the canonical module is closely related to the ring being Gorenstein in low codimension, we also explore quasinormal rings, introduced by W. V. Vasconcelos. We provide several examples as well. ©2025 Walter de Gruyter GmbH,Berlin/Boston.

A degree of a module M is a numerical measure of information carried by M. We highlight some of Vasconcelos’ outstanding contributions to the theory of degrees, bridging commutative algebra and computational algebra. We present several degrees he introduced and developed, including arithmetic degree, jdeg, homological degree, cohomological degrees, canonical degree, and bicanonical degree. For the canonical and bicanonical degrees, we discuss recent developments motivated by our joint works [25, 19, 9]. ©2025 Walter de Gruyter GmbH,Berlin/Boston.

Context. We present an observational and theoretical study of the complex stellar system S1082 in the open cluster M67. This system consists of at least four stars: a blue straggler in a 1.07-day eclipsing binary with a main sequence star (binary A) and another blue straggler in a 1185-day orbit with an unknown companion (binary B). Aims. We analyzed observational data to obtain the orbital and stellar parameters of the components of the eclipsing system. We then explored mass transfer and dynamical encounter scenarios that could explain the derived properties of all of the components of S1082. Methods. We combined high-precision photometry from K2 and TESS with archival light curves, new radial-velocity measurements, and speckle imaging to refine the orbital and physical parameters of the system. To explore the formation pathways, we conducted binary evolution simulations with MESA and dynamical scattering experiments with FEWBODY, followed by a tidal evolution modeling procedure. Results. Our revised radial-velocity solutions yield significantly changed dynamical masses for binary A, reducing the tension with the cluster turnoff mass compared to previous studies. Speckle imaging shows two resolved components separated by 390 AU in projection and, in combination with the two spectroscopic orbits, this is suggestive of a hierarchical quadruple configuration. Our results suggest that the two blue stragglers formed separately, with later dynamical encounters assembling the present configuration. This work underscores the importance of stellar dynamics in shaping the evolution of complex stellar systems within cluster environments such as M67.

Underserved communities face persistent challenges due to limited access to healthcare services. Digital volunteering offers opportunities for healthcare professionals to support these populations remotely. This study examined factors associated with healthcare workers’ intentions to participate in digital healthcare volunteering in Algeria. An extended technology acceptance model was used, incorporating perceived organizational support (OS), altruism, and social responsibility. A convenience sample of 142 healthcare workers completed a survey, and hierarchical regression analysis was conducted. Results indicated that perceived ease of use, social responsibility, altruism, perceived OS, and perceived usefulness were each significantly associated with intentions to engage in digital volunteering. The extended model explained 75.6% of the variance in intention, highlighting the relevance of psychological, organizational, and ethical factors. These findings provide insights for policymakers, healthcare organizations, and developers seeking to support digital volunteering initiatives. Limitations include the cross-sectional design and the use of convenience sampling, which may affect generalizability. Future research should consider longitudinal designs, larger and more diverse samples, and cross-cultural comparisons to validate and extend these findings.