Microwave synthesis of 5-Substituted 1H-Tetrazoles catalyzed by bismuth chloride in water
Resource type
Authors/contributors
- Coca, Adiel (Author)
- Feinn, Liana (Author)
- Dudley, Joshua (Author)
Title
Microwave synthesis of 5-Substituted 1H-Tetrazoles catalyzed by bismuth chloride in water
Abstract
(Chemical Equation Presented). Bismuth chloride was used to catalyze the [2 + 3] cycloaddition between sodium azide with aryl nitriles, aliphatic nitriles, and vinyl nitriles. A number of 5-substituted 1H-tetrazoles were synthesized in water or isopropanol/water mixtures using microwave heating. Good yields were obtained for these reactions when heated for 1 h at 120-160°C in a 3:1 isopropanol/water mixture. A few of the less reactive nitriles required longer reaction times for good yields. © Taylor & Francis Group, LLC.
Publication
Synthetic Communications
Date
2015
Volume
45
Issue
8
Pages
1023-1030
Journal Abbr
Synth. Commun.
Citation Key
pop00032
ISSN
00397911 (ISSN)
Language
English
Extra
11 citations (Crossref) [2023-10-31]
Citation Key Alias: lens.org/144-480-611-110-32X
tex.type: [object Object]
Citation
Coca, A., Feinn, L., & Dudley, J. (2015). Microwave synthesis of 5-Substituted 1H-Tetrazoles catalyzed by bismuth chloride in water. Synthetic Communications, 45(8), 1023–1030. https://doi.org/10.1080/00397911.2014.989451
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